Spyke

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Resistance is futile

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"You owe the companies nothing. You, especially, don’t owe them any courtesy. They have re-arranged the world to put themselves in front of you. They never asked for your permission, don’t even start asking for theirs." Banksy on utilizing ad space.

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Las Vegas' dystopia-sphere, powered by 150 Nvidia GPUs and drawing up to 28,000,000 watts, is both a testament to the hubris of humanity and an admittedly impressive technical feat | PC Gamer

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I don't know about power, but Vegas is actually incredibly water efficient. Due to the way the water rights work with the Colorado river, they're not allowed very much, but it doesn't "count" if you put it back in. So nearly every drop they use is treated and put back (probably cleaner, tbh). Boggles the brain, but somehow it's actually a fairly sustainable city. More than any other other major metro, in any event.

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mycology

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So most fungi do have a lifespan, they have teleomere decay, and when you're cloning mushrooms (from propagating mycelia) you have to let them go to fruit (the part that looks like a mushroom) every now and then. It's a pain in the ass.

But like the other poster said, they play it fast and loose with which part you consider the "organism". My favorite thing is that they do cytosolic streaming. Genetics can be a pain on mushrooms because not only do they share nutrients and metabolic burden through mycelia, they can share nuclei.

One of the weird convienent realities we used extensively is that cells are big enough you can spread them over a petri dish with a little loop, and if you diluted the initial sample enough, the colonies that developed were, practically speaking, from one parent cell. So you could try to modify a bunch, and then plate them (spreading the cells around) and pick individual colonies that were all clones from a single parent. Fungi mycelia means the nucleus isn't stuck in one cell. It also means expression levels can be variable (some cells will have multiple nuclei, and then later maybe they don't).

Fungi are a godamn pain in the ass to study. They're not mysterious, they're not alien, they're just fucking assholes.

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That split entirely ruined the season for me. There's way to much time between seasons, which I get, animation takes time, and they have some big names voice acting. But that split in addition with the long season time meant I could barley remember what was going on and then it was over.

I don't know, it's a great show but I'll probably catch it 5 years from now when it's done. Just boneheaded producing decisions.

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YouTube Channel Linus Tech Tips’ Inaccuracies And Sexual Harassment Allegations, Explained

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Yeah, that one hit me weird also. Like there's videos of him doing installs and stuff at other employees houses, so maybe that's just a culture thing, but it's still weird. Like can you imagine one of the late-night folks making a joke about how the cue card guy screwed up installing his dishwasher, but not meaning it as a joke? Like you don't screw with peoples livelihood.

Like if you had a glass instsall company, and some of your employees did a sloppy job on your personal shower door, you might have a talk with them, implement an improvement plan, etc because it affects clients experiences. What you wouldn't do is put them on blast for views. And that's only because it's relevant to their actual work. Last I checked LTT doesn't offer install services.

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Restaurant Bill

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Restaurants have notoriously thin margins. I'm not defending this bill, and there are definitely awful practices out there, but it ain't easy. Even a $34 dollar steak only kind of covers all the ancillary costs that make it happen.

The biggest issue with the crunch we have going on is that food (prepared or otherwise) should be way more expensive, and that shouldn't be an issue because most people should be making way more money. All of those should/shouldn'ts got way out of whack over the course of decades, and the circus only continued because people found crappy ways to keep it going.

It's a lot of industries. Construction is a great example. The developers make money. The material vendors make money. The builders make money. The sub contractors who actually put the parts together get haggled on invoices and take the lower amount because they have payroll to make and equipment loans to pay. Loans that are happily given out because the equipment can be easily repossessed.

It's a very good thing everything is correcting, but it's going to be an ugly process as workers get their due and pass the burden on to the small business owners.

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Harris picks Minnesota Gov. Tim Walz as her running mate

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I'm a registered libertarian. Despite the craziness, I don't plan on changing that. I wouldn't have voted for Biden, strictly because I live in a state that has 0% chance of flipping, BUT I routinely vote for democrats in senate/house/local races where my vote actually does make a difference. I also encouraged friends with similar mindsets in battleground states to vote Biden.

I think the democratic party needs to fracture, it just needs to fracture AFTER the republican party.

All of that is a setup to say: I also am excited, and if someone like me is excited, I think that's a DAMN good sign. I cannot wait to piss and moan about a Harris admin. It is a big damn country, I look forward to disagreement returning to the point it doesn't result in erosion of fundamental rights and democracy itself, not to mention godamn violent insurrection.

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well, at least I wasn't the only one to wonder

Similar to the meme... godamn did they fuck up by not holding geneticists to something close to... SOME standard naming.

Dated a maternal fetal medicine specialist. She'd come home being like "you ever have to explain to someone they have a mutation in the 'sonic the hedgehog' gene of their kid?!" If you're familiar with what it does in fruit flies (when it was named), it's fucking horrific in humans. Don't google it.

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Because it is, in fact, gen z. I deal with a lot of contractors in a tech field. There's a lot of stuff we do that is prototype/beta level. It's not customer facing. Rough edges are fine, having to reboot it once a day is fine, it just needs to work and if it's not I need to know why.

Gen Z is wayyyyy better at that than millennials. Don't spin me some bullshit, just explain the issues and how much of a headache I'm in for. Previous folks would give me some bullshit about "well it doesn't do that but that's out of scope of our original contract so fixing it is $X/hr on retainment for our expertise and our ability to bring in affiliate partners". Gen Z is much more "man, this shit is cool, but those goal posts shifted, did the best I could, call me if you have issues and at a certain point and I if you're a pain in my ass I'll bill you".

Like they just don't beat around the bush. No spec is ever perfect, and rather than dance around it they'll just be like "I did my best, and I'll go extra until I won't and I'm not really going to bother spending much time explaining to you we're out of scope. You know it. I know it. I ain't dancing because I don't get paid to dance."

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Kamala Harris campaign trolls Trump with video of empty seats at his rally

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I'm sure there are people who have said it before, but Lindsey Ellis did a great essay on mel Brooks, and the whole point of his comedy being "dude... People marching in synchro is just goofy". The point being how damn fragile a facade is when there's nothing behind it, and how much these kind of "strong men" depend on it.

The whole "weird" thing was the perfect shot. The reason it works is because it's also true "no man, you're not to tough for me, you're just... Fucking weird..."