Even worst, my dog got it for free from the public vet university for years. They even gave us the syringes. It's the same human insulin and my dog got it for free. Guess his plan worked better than he thought... only no in the us
the OOC might be TYPE 1 which is even more dependant on insulin than type 2, because you're pancreas cant make any insulin at all. plus there also other expenses that comes with being type 1. CGM, INSULIN pumps(which are often regularly replaced because they wear out). you can sometimes tell when someones type 1, if they have a device attached to thier arm, its usually a circular button, thats the sensor(its another cost)
I’m sure they’re Type 1. At least with Type 2 you can kind of manage it a little without the meds. The insurance company should be firebombed for refusing to replace the damaged meds.
There is plenty of propaganda on social media to exalt the billionaires and CEOs. Instagram is especially really bad at it. I don't know why the algorithm suggest heavily to me about "entrepreneur" pages (maybe my investing platform sold my data), although some of these pages whitewash literal fraudulent and underhanded behaviours from celebrity CEOs and fraudsters, spinning their past behaviours as "another way to get rich". I also think the posts and profiles were written by bots, because the language and syntax used sound almost identical from one another, in spite of these profiles supposedly being independent from one another.
Not if you stayed, then it’s an investment. Money doesn’t just disappear when goes to poor people, they use it to buy things like food and stuff. It would only be a financial drain if you were sending that money back home.
The North American mind cannot comprehend the benefits of supporting the poor.
Perhaps strain would be a better word than drain - it would still be a short-mid term financial burden to take even a tiny fraction of the sane population from the US, it's a big country. Sure would be nice if it could be arranged though...
Don’t worry, there aren’t that many sane people in the US. A lot of them are under the impression that they’re sane because they take the “balanced” position, though, which is to say that they just choose whatever’s in between fascism and barely progressive policy while they call themselves intelligent.
Frankly I’m not sure I’d want a bunch of people who cannot take accountability and who have such main-character energy they think that they would be allowed in while “bad” people wouldn’t be. We have enough problems with similar mindsets here in Canada and I really don’t want more of that except now they’re making it even harder to get away from our useless, conservative, Liberal(capital L) party.
Well that’s the thing, it wouldn’t be possible so the entire idea of “let us sane people come” is flawed from the start unless they truly believe that there should be a purity test and that they would pass it. Anyone who genuinely thinks that way should be immediately disqualified from immigrating based on their own idea of an ideological test.
“I’m different though and there should be actual, real laws to permit to do particular things!” is not the position of someone who considers their community at large to any particularly special degree. And to be clear I’m all for banning hate speech and stuff because that’s a specific banned behaviour and not a specific allowed behaviour, and we have evidence to show that it can be as harmful as any physically violent attack.
It would only be a financial drain if you were sending that money back home.
Only if you limit your view to your nation. 'Back home' across the border it would most likely also buy food etc. And that would be fine.
The real drain is the infinite black hole of the rich guys pockets. That is where all the money is. Don't blame people who send money to their loved ones to help, just because there is a border.
This is correct, though the initial drain might still be too much if there was literally a big exodus all at once. Maybe if the refugees from the US distributed fairly evenly across the various countries it could work?
It is that hard, I’ve looked. You typically need to rank highly on a skill list AND have a relatively well-paying job offer. And if you think it’s hard interviewing in your own country, it’s far worse interviewing outside of it.
Australia and the US have a reciprocal agreement which makes it so any Australian who wants to emigrate to the US can, and quite a few Americans can easily move to Australia. On the America to Australia side it is always oversubscribed, so it's moderately hard to get to Australia. I wonder if timing the application is important.
What are you comparing it to? Americans have a much easier path to permanent residency than a vast majority of the world.
Take a look at the skills lists they aren't that insane. Also you dont need to go straight for permanent residency you can start with a working visa which is easy to get.
In comparison yes, it’s easy. In practice it’s far outside the means of the average American. Hell, more than a quarter of all households in the US are living paycheck to paycheck right now. That’s effectively impossible.
Is a foreign government going to extradite you for missing paperwork and no outstanding tax debts (especially because everyone else thinks it’s nuts that we require nonresident citizens to file taxes)? I guess it’s possible, but it strikes me as very unlikely.
But if you’re still financially attached to the US/likely to visit, they’ve got some power over you.
I’m not a lawyer or an accountant (obviously. This is not best practices)
Why would that strike you as unlikely? It's extremely likely because most countries that people would want to flee to already have extradition agreements with the US.
All the US has to do is declare you a fugitive and those countries will pick you up and ship you back.
Especially with how petty this administration has been.
It's usually too expensive to justify pursuing international cases, nevertheless don't fuck with the IRS lol. That being said, people moving abroad to escape debt, such as student loans is not altogether uncommon.
What do they get out of it? It’s expensive and you don’t even actually owe money. Plus, extradition agreements only cover either things that both countries consider illegal, or a set of very serious crimes, like murder, afaik.
No exit tax. Academia/skilled worker route, I've been beelining an out since I was a teenager and I qualify for EU citizenship on heritage, working on that. I would like to thank my now irl friends from thousands of hours on EU MMORPG servers for unintentionally guiding me out. 👾❤️👾 Love my girlies.
Exit tax is only if you give up your US citizenship, which you definitely can't do if you don't have another citizenship and even then it's very often not required
the one that have money to migrate to another country have done it already. buts mostly PHD level professionals, rather difficult for people who only have a ms or bs with no established career already. unless you well off enough to be able to move.
it would probably have to be millions, or 10s of millions (around 40ish million) suddenly moving out of the us, then the usa and that would would see real impact on brain drain and economy(especially the ones in key stem sectors, at some point it will affect israel pipelines(weapons tech and research, like MIT) from university), but then again most people are too content in the usa, and the massively propagandized people us has practically pacified them, and essentially made a cultural bubble of selfishness(hate taxes, guns,,,etc. propaganda)
Yea I guess but my mom was destroyed by our cruel and heartless system. She’s gone now but painting this helped me reconnect with the glimmer of hope we all felt for a moment after this happened. It also helped process the trauma I myself went through as her caregiver not being able to access what she needed
I am so, so sorry about your loss. I'm glad to hear that you were able to feel a beacon of hope last year, and that this painting was a way for you to cling on to it and feel it a little longer. I hope you find a way to keep holding on to it, and through that hope find the courage to not give up and try to support change instead whenever you can and have the strength and energy to do so. But I can't even imagine how hard that must be. And most of all, carry the love you had for your mom in your heart despite the grief, and the disgust and hate for the system that led to her demise quicker than it had to be.
I hope you don't mind if I save that picture of yours.
Symbols are powerful things. I'm not an American, but something that surprised me with Mangione was how people on the left and the right seemed to support him. It was a rare case of example of political unity amongst regular people.
It was incredible how right wing pundits were so disconnected from their audience, trying to promote outrage while their audience would have been popping champaign of they could afford it
California is contracting its own insulin supply and it'll be available for $11 a pen starting Jan 1, 2026. I know not every state can or are willing to do this but just throwing out some examples and hopefully optimism to somehow fight the American decline from within it. We're in a unique position as our state economy is larger than most countries but I am hopeful we will throw our weight around to counter the bs. https://www.chhs.ca.gov/blog/2025/10/17/governor-newsom-announces-affordable-calrx-insulin-11-a-pen-will-soon-be-available-for-purchase/
Seems like something other states should get in on. Now that the program is established seems like it would not be as hard to pay into it and get a share of the product.
theres only 3 companies that produce it , Eli Lily, sanofi aventis and novo nordisk, they have fought aggressively through litigation in the past to prevent any insulin generic, or biosimilar to reach the market. they agreed amongst themselves to have whatever the cost they want without competing with each other.
They are, actually. The point of patents and copyright is not to protect the creator- that's a temporary effect. The point is to release the thing to the public afterwards. The problem is that capitalism corrupts the process and finds ways to make the temporary effects permanent. Disney has succeeded in making copyright last effectively forever.
Something I've noticed is when untraveled people in the USA try to contextualize themselves with other countries they pick the worst examples they can think of. Favelas in Brazil or slums in South Africa for example. We do this to the point where our entire conception of countries (or in the case of Africa, continents) is the worst imagery we can think of. I think they genuinely don't believe that, for all their troubles India, Brazil, Mexico, Nigeria, etc also have smartphones and big buildings and libraries and universities and laboratories, and educated people living decent lives.
They also can't see how the overcrowded jails full of pretrial prisoners, the barefoot children carrying buckets for water in Appalachia, the rundown schools full of illiterate kids, the impunity of rich private interests, the corrupt sheriffs and judges, and on and on, puts us in the company of the "third world countries". Yes we have nice places too, but SO DO THEY. A broken society in the 21st century isn't people living in mud huts, it's children shitting in the street next to a glass skyscraper with LEED Platinum certification.
And it's not just "overcrowded jails full of pretrial prisoners, the barefoot children carrying buckets for water in Appalachia" but the grad students in LA living out of their cars, or grandpa sleeping on a bus stop, or people in the Rockies surviving off roadkill and forage.
Seattle tent cities/tiny homes make some Favelas look real swanky.
Logically, it's not about how much money you make, it's about purchasing power. It is irrelevant if you earn only $400 a month when you can eat well for $1 and pay $100 for your housing, you have free health care and education. That is the reality in some third world countries.
Strictly, technically every other way China is still third world. This concept of third world being poor seems to have originated from the common charity ads in the 90s and 2000s who loved the phrase, and from the American exceptionalism that thinks everything not American is dirty and poor.
Being poor is the only way a country is third world or not. Being politically related to America is not relevant to the present definition. So no, it is not "technically in every other way". It just is not a third world country, period.
You're right that they either never learned what 1st-2nd-3rd world really means, or they forgot what they were taught in history class. Unfortunately it still is the main term to refer to poor countries even though it's incorrect. Language seems to be biased towards the common meaning over the technically correct meaning.
Spain isn't third world, it already had shown the middle finger to Trump and also has few to do with Rusia. Third world countries don't certainly mean people starving, the people there often have all what they need, but this, you'll see few Ferraries there and chalets with swimming pool. Someone is rich, not necesarly because a lot of money, but because he need only few. We often enter in a rabbit hole of the consumism, spending a lot of money in things we really don't need, we work like a dog to have enough money to pay a journey to Hawaii to recover us from the burnout, which we wouldn't have working less, no needing this journey.
Have you been to Spain? I'm not saying it is not better than where the US is headed to, but it's a "western" country in Europe, with all the issues that come with it. Somewhat social market economy, but still suffering from the usual issues, including people driving Ferraris while others sleep on the street.
Also, at least since Franco I don't think anyone genuinely thinks of Spain as third world.
Well, I'm from Spain, also in Spain there are People with Ferraries (few) and also poor people, but there is nobody without food, because Spain has a strong social system and free healthcare for everyone. Nothing, absolute nothing to do with the US, it's the opposite in almost everything. Luckily Spain has also little dependency on the US or Rusia, so it is also not much affected by Trumps Tariffs or Rusian Gaspolicy. Trump hates Spain.
If you can eat well for $1 then it is definitely a poor country relative to the US. Differences in purchasing power are a direct result of differences in wealth.
I think that the US is a third world country, it's rich but most money is used for weapons and to make richer the billonairs and big corporations, in the social and cultural sphere, it is one of the most backward in the world. Now with Trump the US is turning in a running gag for the most countries. A country where 40 milloncof citizen don't have enough to eat at least 2 times a day, isn't a rich country.
USA is an total dystopic country, any Banana Republic has more culture. US is only powerfull because use all the money for weapons, developed by foreigner scientifics. First world is anything else.
You will say that the US is a first world country, it's better for your health
Not really. Poverty rates are higher, yes, but many middle income third world countries do have sizeable and growing middle classes. They're called developing countries for a reason. The image of war-torn African countries where everyone works in mines isn't really representative.
the problem is that there is natural (as in, unmodified) cheap generic insulin available, it's just that it sucks compared to everything else. you see, insulin is a peptide that is supposed to appear, do some signalling, then disappear and unmodified insulin copies this thing exactly. the problem is, most of the time when peptide is supposed to work as a pharmaceutical, you don't want to do that, you'd like insulin to last longer than usual, which means changes to it that make breakdown slower, or adding something that makes it stick to albumin, which has similar effect because it hides insulin somewhere enzymes can't reach it and also it makes it start acting slower. this means less frequent dosing and less changes in insulin activity over time. there are also other insulins that start acting faster than natural, and this is also due to a couple of modifications in its structure
for another example, ozempic was not the first drug in its class, it's also a modified peptide, and it can be injected s.c. once a week, compared to previous iteration (liraglutide) that requires daily injections. if natural peptide is injected i.m. instead, its halflife is half an hour, and in serum it's only two minutes (it gets released a bit slower than it is metabolized)
manufacturing costs are about the same for any variant, most of it is in purification. patents for a couple of these have expired anyway by now, but if manufacturing is limited then price can be set arbitrarily high (see daraprim)
i mean i don't think about it as a separate budget line because if you don't have that you get police raids and investigation instead of normal business, but yea. insulin is purified using HPLC, so at all times you get some of analytical data about fractions you just made, so some of QC, not all, but already something, already happens at this point
my point is that actual manufacturing costs will be low because biotech scalability logic is that you need to make yeast or something that makes peptide you like and then all you need to do is keep bioreactor alive and happy. lots of what is left is in purification
also it's an injectable so it's gonna be kept to some standards that non-injected drugs aren't. whoever comes up with insulin pill will be printing money
there are multiple short-acting and long-acting insulins because you can't patent other people's things, but now it's all off-patent. just take your stainless steel bioreactor and preparative HPLC, cook up a batch, wait ten years for biosimilar approval and you're good to go
because unlike with small molecule drugs, when cooking up generic biopharmaceutical there’s extra approval process that amounts to a tiny clinical trial https://en.wikipedia.org/wiki/Biosimilar this and type of economics of scale that there is with biologicals makes manufacture at large scale way more preferable. these requirements were loosened a bit over time
Correct, but when it's already been established that people will pay those prices, they keep them high. So instead of going from $800 to $5 out of the goodness of their hearts, they go from $800 to $650 (number made up) to get more business but still make massive profits.
Every time someone talks about you being supposedly free to choose where to work they should get instant diarrhea. Let alone medicine of course, that's a hard dependence.
Nobody is truly free without proper UBI and free healthcare and good public transport. Only then true freedom can exist.
instant diarrhea, haha, but yeah, it carries the point across quite well. some people can't work wherever they want, at whatever job they want, because they have health conditions limiting their range.
A lot of the benefits people associate with capitalism require a free market. The US problem is that the megacorps have gotten sufficiently powerful to abolish that free market through regularory (and legal) capture, enabling entrenched monopolies.
Look, mate, Intellectual Property Laws are literally the government creating and giving somebody an artificial monopoly on something which would not naturally exist if it wasn't for artificial limitations on "doing the same thing" being forced on everybody thanks to legislation and the coercive powers of the Legal system, and this was purposefully written in Law to do exactly that, so it's not an unexpected legislative side effect.
So anywhere were Intellectual Property legislation can apply the market is not free, on purpose and by policy.
Now, a good argument can be done about how IP law incentivises the creation of things with a high utility value which would otherwise not be created, but that doesn't alter the fact that the whole thing is a giant legislative sledgehammer with massive destructive capability for both the Economy and people's lives, which needs to be handled very carefully in order not to do more harm than good.
As it so happens IP has gone completelly out of control in the US because Corruption there is incredibly high, more some when it comes to the property of ideas since holding a piece of such property can yield billions of dollars in profits - the profits from owning ideas can be far vaster than of merelly owning land - and this shit has been copied around the world by almost as corrupt politicians (for example, the thoroughly corrupt crooks in the EU commission pretty much copy every single "this will make me personally lots of money from thankful corporations" pieces of legislation from the US).
So Copyrights now last an insanelly long period - about 1.5 times the average human lifetime - before things covered by it go into the Public Domain, whilst lots of Patent Offices (most notably the ones in the US and Japan) will just accept patents on everything no matter how obvious without even a proper search for prior art, hence things like the "round corner button" patent that Apple has as well as countless business patents for "solutions" which are obvious to any domain specialist (many such patents literaly the product of paying a domain expert for an hour of their time by a patent troll to just "think up a solution for this" as no actual implementation is needed to get a patent, just the idea of how it could be done).
All this to say that this fucked up situation of insane government-given monopolies all over the place for shit that's obvious to domain experts or derivative (a common trick in patents for medicine is to just do a small tweak in the formulation to get another 25 years of patent protection on pretty much the same thing) was created ON PURPOSE by the very politicians who claim to want a Free Market.
The entire thing should be reviewed and ajusted in exactly the opposite direction it is going (so we should have shorter protection periods, no "ideas only" patents, proper prior art searches rather than relying on expensive court cases to nullify patents on things somebody else already did or which are common practice in that industry, no business patents, properly funded Patent Offices, no transnational recognition of patents - so that countries *cough* Japan *cough* can't just use their Patent Office as some sort of commercial weapon to benefit their local companies in other markets - and so on) but given that Intellectual Property is an area worth trillions (and, remember, it's entirelly artificial, so without that legislation such property would be worth nothing at all) and politicians are incredibly corrupt nowadays, this shit is getting worse rather than better (and, IMHO, severely slowing down the speed of progress in the current Era versus a Free Ideas system)
Sectors like pharma require enormous R&D budgets. If you have a free market with many companies, each company will have only a tiny marketshare, and therefore only a tiny budget. So you can't do without the megacorps. The solution is for the megacorps to be run by the government / non-profits / trusts, or, if that is not possible, for prices to be fixed by an independent regulatory body.
Yup, but their products don't work as well, don't work for everyone, or have other downsides. Banting's original insulin would be dirt cheap today, but it's shit compared to what we have now, so the best products on the market today charge a premium for either efficacy or convenience.
Reminder that the term Stockholm Syndrome was coined to blame victims for being rightly more afraid of the police than their captors:
In [Jess Hill's] 2019 treatise on domestic violence See What You Made Me Do, Australian journalist Jess Hill described the syndrome as a "dubious pathology with no diagnostic criteria", and stated that it is "riddled with misogyny and founded on a lie"; she also noted that a 2008 literature review revealed "most diagnoses [of Stockholm syndrome] are made by the media, not by psychologists or psychiatrists." In particular, Hill's analysis revealed that Stockholm authorities, responded to the robbery in a way that put the hostages at greater risk from the police than from their captors (hostage Kristin Enmark, who during the siege was granted a telephone call with Swedish Prime Minister Olof Palme, reported that Palme told her that the government would not negotiate with criminals); as well, she observed that Bejerot's diagnosis of Enmark was made without ever having spoken to her.
Otherwise, we probably agree that AmeriKKKans are a feckless, servile people.
Mod note: Do not make personal attacks towards this user, lest I have to slap more knuckles with a ruler. You can engage with the critique respectfully, or it's 📏 time.
Stockholm syndrome is a proposed condition to explain why hostages occasionally develop a psychological bond with their captors. It is named after an attempted bank robbery in 1973, in Stockholm, Sweden
My comment was in response to a comment about AmeriKKKans having "Stockholm Syndrome", which as it turns out is not a real or valuable diagnosis. However, I do not disagree with the implied critique of AmeriKKKan people as being feckless and servile people.
A: It completely undercuts the seriousness of your comment and makes the whole thing come off as a tirade by an edgy teenager.
So you disagree with the tone and not what I'm saying? Because if so, that sounds like a "you" problem, i.e. you're more interested in the tone of a message than its content.
B: Jokes don't get funnier every time you repeat them, it was mid the first time and eye roll worthy by the 3rd.
It's not a joke and it's not supposed to be funny. I genuinely hate the USA and everything it stands for.
Nils Bejerot was a total hack. He tried to ban comic books, and later transcribed that same energy in a war on drugs that has resulted in some of the worst health outcomes for drug users in Europe. Unfortunately his ability to be confidently incorrect swayed a lot of gullible rubes, and his legacy still casts a shadow over Sweden to this day.
AmeriKKKa is a settler-colonialist project, and the entity and its defenders deserve zero respect. I mentioned AmeriKKKans because the person I replied to used Stockholm Syndrome to critique AmeriKKKans on a post critiquing the AmeriKKKan healthcare system, so critiquing AmeriKKKa is relevant here. And I don't like spelling AmeriKKKa as part of USA correctly because (1) places like Central America and South America should be distinguished from the United States of AmeriKKKa, and (2) it offends the people who need to be offended, i.e. people who still feel affinity for the AmeriKKKan project and people who tone-police others who are just brutally honest in speaking their minds.
You are literally posting from an anarchist Lemmy instance, why TF is this controversial to you?
Fine, just do Ctrl+F, replace each instance of AmeriKKKa with {insert preferred term for the United States}, and move on with your life. Like I'm not even trying to get you to say it, I'm just saying it. It's almost like you have a problem with what I'm saying and not just how I'm saying it...
Services that are necessary for life (like healthcare)...if other countries have figured out how to make it affordable/free (at point of use), any person or industry that tries to extract profit out of it is literally anti-American.
The insulin produced now has benefited from advances in technology just like most things. The fast acting insulin is predictable and works in 45 minutes to an hour and a half. The original insulin took hours and wasn't nearly as predictable or stable. Testing/monitoring technology has seen even more significant advances.
I owe Banting and his colleagues my life, but it is different. That's not to say that the continued well being of the public should be profitable and exclusive.
I mean insulin is about 10x more expensive in the USA compared to other Western countries. It's cheaper still in lower income countries. Many European countries also have a price ceiling for medication, so your monthly cost for life-saving drugs is capped.
I don't know exactly why a manufacturer doesn't set up production for much cheaper generics in the USA, but for whatever reason Americans are getting price gouged like Satan doesn't believe in tomorrow.
To be fair, most Americans agree with the capitalist first approach right up until it affects them individually. If they were willing to help each other instead of believing that anyone other than themself is a freeloader and lazy, they would have the support that other countries take for granted.
It was sold to a Canadian public university to manage the patent for public good.
They have, everywhere else in the world basically, insulin costs pennies.
In America, they have been able to patent certain formulations and delivery methods, and they keep making marginal modifications to string the patents out to keep Americans locked in to absurd insulin prices.
Was that the answer you thought it was going to be?
I can confirm, as a insured I am paying $0.00 for Insulin in Macedonia. Now I am receiving 6 Novo Nordisk Tresiba pens per month. How much is that in US?
I couldn't find the answer easily myself and ended up asking AI, so take this with a significant grain of salt, but supposedly a 3mL pen would be around $145 without insurance. If anyone can find a better source, I'd be all ears.
They also don't make insulin the way that he did back then. Not justifying the price hike cause the way its made now is way cheaper than it was with the old method (which was basically grinding up animal parts to extract insulin). These fucks are just profiting off of the suffering of Americans who have literally no choice but to use their drug.
Remember, the 1920s is long ago. Giving the patent to the equivalent of a non-profit organisation was probably better than disclaiming it, since it's easier to have one large, well-known entity that will fight off people trying to re-patent it than to disclaim it and hope that no patent clerk ever lets a fraudulent re-patent go through.
In 1920 you couldn't just google for prior art when fighting a fraudulent patent.
Nowadays you just google for other patents and done. But back then, I guess that searching for prior art was quite a lot more difficult. Gifting the patent to an university so that they defend open access to the patent sounds like a more reliable plan.
I mean, even nowadays patents are greenlit my patent offices even though there's clear prior art (Nintendo's recent patent for catching monsters in a ball in a game comes to mind, which Nintendo would have to have patented before publishing their first game with that mechanic around 30 years ago), and even today it's really difficult and expensive to get such a clear nonsense patent invalidated.
So difficult that e.g. Palworld opted to change the mechanic instead of fighting the patent.
So I do understand why someone would instead gift the patent to an university under the condition that they keep access to it open, especially 100 years ago.
The difference is that in the case of transferring the patent to the university, there's a legal department at the ready to defend the patent. The same is not the case for a disclaimed patent.
I believe there are some restrictions on mailing insulin across the border due to regulations and customs laws. However, there might be ways around it if you're willing to do a little research and possibly pay extra fees.
people have been crossing to canada for cheap insulin drugs, the same one made by the trioply insulin companies via driving. other healthcare options, like dental work or medical procedures, they will be seeking places like thailand, mexico, india(the cities that cater to medical tourism)
fyi this fella has no training in chemistry or medicine and is just some random ass programmer with severe case of "saving the world from my homelab" symdrome
Were I am, you just get Insulin for free with a prescription from you Family Doctor, because we have a National Health Service.
Even without said prescription, it's only €70.
Americans are being thoroughly screwed, and it's very much on purpose thanks to the way laws and regulations around Healthcare were designed in the US (and, at the risk attractint the crowd throwing "bothsideism" slogans around to defend "their" "tribe", this is due to the actions of both US major parties) since in a real Free Market, Insuline over there should cost around the same as it costs over here without a prescription, not 10x more - without artificial market barriers there would be investors literally flying planeloads of the thing from Europe to US to make a killing out of buying it cheaply over here and selling it for "merelly" twice as much over there.
In Canada it is still considered expensive, but not even close to $800/month. It's only considered expensive because most shit like that is free or a very nominal fee, but repeated need is what it is.
Also I just remembered, I used to have United Healthcare and they didn't cover this medicine so I had to switch. Had to pay ~$300 for that refill (i think it was fewer tablets and 75mg that time). $40 on my current insurance.
Is there any reason a diabetic has to get the newer patented formulas instead of the old one that the pic talks about which is regularly sold for around $25 a vial in the US without insurance?
I know the new stuff works faster and you don't have to worry about your diet as much so I'm sure it's much easier, but why would you have to die instead of just managing your diet and using the $25 stuff for a month in this emergency situation?
Don't get me wrong all medicine should be free and stuff but like, why die instead of switching to the cheap stuff and dietary management for a month?
Insulin is not permanently shelf stable, and will still expire in the fridge.
Diabetics usually start with a long-acting insulin to keep blood sugar from naturally rising plus a fast-acting insulin for corrections and to compensate for food.
The old style of just giving 2 long-acting shots of mixed insulin is mostly obsolete, except for legacy patients, some pregnant patients, and other special cases I can only theorize.
A good number of diabetics only use fast acting insulin in a pump, receiving microdoses every minute.
To switch brands of insulin, much less therapies in any circumstance requires a doctor's visit.
With all that said, the insurance company will often replace a medication in the event of an accident, typically only once a year.
Without that, a patient might be able to find a charity they will assist them.
You also may be able to travel to the next state over where the cost of insulin is regulated.
Failing all other options, it is better to check yourself in to the hospital as your sugar begins to rise and tell them that you cannot control your blood sugar.
Unless I had already reached my annual deductible, that is.
"Hey good news! After about 35% of your annual income is spent on medical bills on top of your triple digit monthly premiums... That health insurance starts to kick in!"
It truly is amazing how an entire industry makes billions by literally avoiding delivering the most basic service it's paid for at every possible turn.
This is not even good capitalism. Capitalism was intended to provide efficient solutions through competition. This is an oligopol secured by generous bribes
The extra ridiculous thing is how they deny services that a doctor says are medically necessary… and not even in a reasonable way, in an abusive way. Like the system that automatically denies 60,000 things an hour or whatever, and count on people wasting tons of time to challenge it. Or when they have an ophthalmologist review your kidney disease and say that some treatment isn’t warranted. And that’s even after you’ve paid your stupid deductible costs for the year.
Not sure about that, and not sure if I could trust that.
Another option is to have the doctor prescribe insulin pens or another brand of the same kind of insulin. It's technically a different prescription and the insurance company usually covers it.
People respond wildly differently to different types of insulin and it isn't just a matter of switching and watching your diet. Too much and too little insulin can be deadly and it makes you feel like absolute shit.
Ah, so you'd need to know your dosage for that type beforehand, and if you didn't know it you can't just wing it. Still though, might be beneficial to know that for emergencies like this because it sounds preferable to certain death.
There should be a little chart your doc gives you at diagnosis (or something, spitballing here) that lays out the dosages you'd need for X, Y, and Z brands so that if say you use X and they're out (or your kid freezes it or something) you can just consult the dosage chart and get Y for now.
The old formulas you can buy OTC for $25 are more inconvenient to use, but will indeed keep you from dying. The main difference between the R insulin and Novolog/Humalog are how quickly they act. Novolog starts lowering your glucose in about 60 minutes while the R takes 2 hours. Dietary management is not related to which insulin you’re using, at least for type 1. The long acting substitute, NPH, is a lot more difficult to use than Lantus though. It still works. I ran out of good insulin on a trip last year and had to sub the R and NPH and did have some issues with hypoglycemia. I’m more qualified to swap them on my own than many people though (lots of people are not informed enough to change their dosage without professional medical advice).
So yes, the claim that OOP’s only alternative to paying $800 was to die is not true.
I really don't get it. If it was in the freezer, why will it be damaged when put back again? Is it that once defreezed some reaction goes on and shouldn't be stopped? I really don't get it. Would it be better to keep it outside the freezer once it warm up?
It degrades from the freezing process and then dosage becomes unpredictable and thus dangerous. If you have insulin it's got big words on it saying don't.
Heres the side of some humalog:
DO NOT FREEZE. Store refrigerated at 36°F to 46°F [2°C to 8°C] until time of use. Store in-use vials refrigerated at 36°F to 46°F [2° C to 8°C]. If refrigeration is not possible, store at room temperature (up to 86°F [30°C]). Protect from direct heat and light.
I’m sure an experienced medic in an emergency could work with it somehow, but for the rest of us living in civilization, insulin that has been outside their recommended temperature range is very dangerous.
Long-acting insulin has crystals that dissolve at body temperature over time, hence it can gradually release insulin over hours. If you break or dissolve those crystals by freezing/thawing/overwarming, the best scenario would be that it became fast-acting insulin, and it would crash your glucose instantly on injection of your usual dose. The worst scenario is that it no longer acts like insulin.
Other way around. The removal of the prolonged release is what would kill you right away. Hypoglycaemia kills WAY faster than hyperglycaemia. Like - one takes minutes, the other one hours to days).
For Australian diabetes patients the insulin Fiasp is $31.60 on the PBS, but Americans pay $930, while the medication Jardiance is $619 to $698 in the US compared to again $31.60 for the 220,000 Australians who access it. (I'm on Jardiance)
:::spoiler Needs text alternative.
Images of text break much that text alternatives do not.
Losses due to image of text lacking alternative such as link:
usability
we can't quote the text without pointless bullshit like retyping it or OCR
some users can't read this due to lack of alt text
users can't adapt the text for dyslexia or vision impairments
systems can't read the text to them or send it to braille devices
web connectivity
we have to do failure-prone bullshit to find the original source
we can't explore wider context of the original message
authenticity: we don't know the image hasn't been tampered
searchability: the "text" isn't indexable by search engine in a meaningful way
fault tolerance: no text fallback if
image breaks
image host is geoblocked due to insane regulations.
Contrary to age & humble appearance, text is an advanced technology that provides all these capabilities absent from images.
:::
Did they try looking for discounts from patient assistance programs from the manufacturer?
They'll reduce the cost to $35.
Manufacturers try to shakedown insurance companies for obscene pay without affecting the amount individuals pay, so they offer those programs directly to individuals.
Not saying this good, just how the system works.
i think thats recent, because eli lily, novo nordisk, and sanofi aventis originally had a TRIOPLY on insulin, they got scared because California was planning to making thier own version lowering the cost. originally they dint do that, and vials were hundreds of dollars.
biologic medication does something similar, like a coupon for thier EXPENSIVE medication, even with it, the cost is still pretty high.
No. They kill us. They murder people. Make it clear why this is happening, why any negotiation starts with every billionaire shot in the gut and left to bleed out, as a compromise.
You seem to think any of those people are competent. They generally are not. The fear, the obedience, is why they can control hundreds of millions with a few thousand thugs. Fuck your obedience.
If I'm remembering the original sysntesis for insulin used dogs, and it was harvest from them after being killed. It's unjust that insulin is so expensive, but also modern production methods are not the problem here. It's greed.
Meanwhile, 10 euros per vial here in Europe. At least his original plan for widespread and easy availability has partially succeeded.
In civilized countries at least.
In brazil 36 reais (about 6 euro). The US is a joke. (And im 99% sure you can also get it for free if you use the public health network)
I have mental health disabilities in the USA and my meds are at zero cost because I literally have had absolute zero income for the past 5 years.
You wouldn't believe how much those mood stabilizer/antidepressant cocktails stack up proportionally when I was able to scrape by on $15 an hour.
The system set me up to fail with how shitty it is, if healthcare wasn't crap I could be contributing to society without crippling myself.
Even worst, my dog got it for free from the public vet university for years. They even gave us the syringes. It's the same human insulin and my dog got it for free. Guess his plan worked better than he thought... only no in the us
Free on the NHS in the UK. In fact, diabetes is one of the conditions that qualifies people for free prescriptions across the board.
It did succeed, humanity just didn't take the win and run to keep it going.
Canadians: invented drug and patent it freely
Americans: Finds way to kill the most people possible while making the most amount of money
To be fair, the killing isn't the point; they're the product. Its just that profit is God, so killing in its name is justified.
Killing poors for the joy of it? That's just an evil bonus.
Killing me soupy with his words.
I’m not diabetic and the situation with insulin fills me with a white hot rage.
Same
the OOC might be TYPE 1 which is even more dependant on insulin than type 2, because you're pancreas cant make any insulin at all. plus there also other expenses that comes with being type 1. CGM, INSULIN pumps(which are often regularly replaced because they wear out). you can sometimes tell when someones type 1, if they have a device attached to thier arm, its usually a circular button, thats the sensor(its another cost)
I’m sure they’re Type 1. At least with Type 2 you can kind of manage it a little without the meds. The insurance company should be firebombed for refusing to replace the damaged meds.
The sensor is no guarantee. Quite a few low carb dieters use constant glucose monitors (CGMs) to identify which foods they should avoid
If you talk about killing the few people like these that are the root cause of all these problems, you're a terrorist. You go to jail
These people actually kill people by the thousands, millions, and we call them smart CEO's and celebrate them 🥂
Free Luigi.
There is plenty of propaganda on social media to exalt the billionaires and CEOs. Instagram is especially really bad at it. I don't know why the algorithm suggest heavily to me about "entrepreneur" pages (maybe my investing platform sold my data), although some of these pages whitewash literal fraudulent and underhanded behaviours from celebrity CEOs and fraudsters, spinning their past behaviours as "another way to get rich". I also think the posts and profiles were written by bots, because the language and syntax used sound almost identical from one another, in spite of these profiles supposedly being independent from one another.
Where's all the promo for hard working Italian plumbers these days?
its in films, and shows especially sprinkled with copagandas, and military propaganda.
I wonder if all the sane Americans did a mass exodus to Canada, Europe, UK, Australia etc, what effect that would have
A lot of us would need financial sponsorship. So there'd be a literal financial drain on those economies.
I still would like to sign up.
Not if you stayed, then it’s an investment. Money doesn’t just disappear when goes to poor people, they use it to buy things like food and stuff. It would only be a financial drain if you were sending that money back home.
The North American mind cannot comprehend the benefits of supporting the poor.
UBI should be ubiquitous.
UBI = Universal Basic Income
Amazing Americans say with their full chest this is socialism
Perhaps strain would be a better word than drain - it would still be a short-mid term financial burden to take even a tiny fraction of the sane population from the US, it's a big country. Sure would be nice if it could be arranged though...
True.
Don’t worry, there aren’t that many sane people in the US. A lot of them are under the impression that they’re sane because they take the “balanced” position, though, which is to say that they just choose whatever’s in between fascism and barely progressive policy while they call themselves intelligent.
Frankly I’m not sure I’d want a bunch of people who cannot take accountability and who have such main-character energy they think that they would be allowed in while “bad” people wouldn’t be. We have enough problems with similar mindsets here in Canada and I really don’t want more of that except now they’re making it even harder to get away from our useless, conservative, Liberal(capital L) party.
Ah yes - subjecting ideological refugeess to arbitrary purity tests, a true classic.
Well that’s the thing, it wouldn’t be possible so the entire idea of “let us sane people come” is flawed from the start unless they truly believe that there should be a purity test and that they would pass it. Anyone who genuinely thinks that way should be immediately disqualified from immigrating based on their own idea of an ideological test.
“I’m different though and there should be actual, real laws to permit to do particular things!” is not the position of someone who considers their community at large to any particularly special degree. And to be clear I’m all for banning hate speech and stuff because that’s a specific banned behaviour and not a specific allowed behaviour, and we have evidence to show that it can be as harmful as any physically violent attack.
And a hell of a good one. Adults will have already passed through education, so we would save on that part.
I get that, the initial investment would be pretty significant.
I'm not against it of course, I just think it's necessary to understand the risks of any gamble.
Only if you limit your view to your nation. 'Back home' across the border it would most likely also buy food etc. And that would be fine.
The real drain is the infinite black hole of the rich guys pockets. That is where all the money is. Don't blame people who send money to their loved ones to help, just because there is a border.
This is correct, though the initial drain might still be too much if there was literally a big exodus all at once. Maybe if the refugees from the US distributed fairly evenly across the various countries it could work?
Have you looked into what it takes to get a permanent visa to one of those countries? It’s not easy.
Its prohibitively impossible.
Its not that hard especially for an American.
It is that hard, I’ve looked. You typically need to rank highly on a skill list AND have a relatively well-paying job offer. And if you think it’s hard interviewing in your own country, it’s far worse interviewing outside of it.
Australia and the US have a reciprocal agreement which makes it so any Australian who wants to emigrate to the US can, and quite a few Americans can easily move to Australia. On the America to Australia side it is always oversubscribed, so it's moderately hard to get to Australia. I wonder if timing the application is important.
What are you comparing it to? Americans have a much easier path to permanent residency than a vast majority of the world.
Take a look at the skills lists they aren't that insane. Also you dont need to go straight for permanent residency you can start with a working visa which is easy to get.
In comparison yes, it’s easy. In practice it’s far outside the means of the average American. Hell, more than a quarter of all households in the US are living paycheck to paycheck right now. That’s effectively impossible.
I did it a while ago, would recommend.
Aren't you still paying taxes to the USA? Just curious.
You have to earn over something like 100k+ for the US to tax you. Salaries are lower here.
Ohhhh that's interesting.
You still have to file, but you don’t need to pay taxes unless you’re earning enough that the visa won’t be a problem.
But, like, if you close everything out and never go back…
The IRS will still find you lol
But then what?
Is a foreign government going to extradite you for missing paperwork and no outstanding tax debts (especially because everyone else thinks it’s nuts that we require nonresident citizens to file taxes)? I guess it’s possible, but it strikes me as very unlikely.
But if you’re still financially attached to the US/likely to visit, they’ve got some power over you.
I’m not a lawyer or an accountant (obviously. This is not best practices)
Why would that strike you as unlikely? It's extremely likely because most countries that people would want to flee to already have extradition agreements with the US.
All the US has to do is declare you a fugitive and those countries will pick you up and ship you back.
Especially with how petty this administration has been.
It's usually too expensive to justify pursuing international cases, nevertheless don't fuck with the IRS lol. That being said, people moving abroad to escape debt, such as student loans is not altogether uncommon.
What do they get out of it? It’s expensive and you don’t even actually owe money. Plus, extradition agreements only cover either things that both countries consider illegal, or a set of very serious crimes, like murder, afaik.
I hear ya but I wouldn't put it past the government. You're now a bargaining chip in future negotiations
If you don't mind sharing, did you have to pay the exit tax? Actually, what was your way out?
No exit tax. Academia/skilled worker route, I've been beelining an out since I was a teenager and I qualify for EU citizenship on heritage, working on that. I would like to thank my now irl friends from thousands of hours on EU MMORPG servers for unintentionally guiding me out. 👾❤️👾 Love my girlies.
Exit tax is only if you give up your US citizenship, which you definitely can't do if you don't have another citizenship and even then it's very often not required
It's already happening, there's been a deluge of affluent people leaving the US.
We're still at the stage where it takes considerable privilege to just leave everything behind and pay the exit extortion (40% of all your shit).
Once things get worse and people have nothing to leave behind you'll start seeing the engineers/doctors escaping.
the one that have money to migrate to another country have done it already. buts mostly PHD level professionals, rather difficult for people who only have a ms or bs with no established career already. unless you well off enough to be able to move.
it would probably have to be millions, or 10s of millions (around 40ish million) suddenly moving out of the us, then the usa and that would would see real impact on brain drain and economy(especially the ones in key stem sectors, at some point it will affect israel pipelines(weapons tech and research, like MIT) from university), but then again most people are too content in the usa, and the massively propagandized people us has practically pacified them, and essentially made a cultural bubble of selfishness(hate taxes, guns,,,etc. propaganda)
Please no, there's already people rioting over 3rd world citizens immigrating here, we don't need to add Yanks to that group too
Remember Remember the 4th of December
Making an AI meme of Luigi as a Saint is one thing.
Making a painting and having it casually displayed in your room is a whole other level.
Also, I can't believe it's already been a year.
Yea I guess but my mom was destroyed by our cruel and heartless system. She’s gone now but painting this helped me reconnect with the glimmer of hope we all felt for a moment after this happened. It also helped process the trauma I myself went through as her caregiver not being able to access what she needed
I am so, so sorry about your loss. I'm glad to hear that you were able to feel a beacon of hope last year, and that this painting was a way for you to cling on to it and feel it a little longer. I hope you find a way to keep holding on to it, and through that hope find the courage to not give up and try to support change instead whenever you can and have the strength and energy to do so. But I can't even imagine how hard that must be. And most of all, carry the love you had for your mom in your heart despite the grief, and the disgust and hate for the system that led to her demise quicker than it had to be.
I hope you don't mind if I save that picture of yours.
Thank you for the kind words yes no problem
Symbols are powerful things. I'm not an American, but something that surprised me with Mangione was how people on the left and the right seemed to support him. It was a rare case of example of political unity amongst regular people.
Yeah I noticed this too
It was incredible how right wing pundits were so disconnected from their audience, trying to promote outrage while their audience would have been popping champaign of they could afford it
✊
California is contracting its own insulin supply and it'll be available for $11 a pen starting Jan 1, 2026. I know not every state can or are willing to do this but just throwing out some examples and hopefully optimism to somehow fight the American decline from within it. We're in a unique position as our state economy is larger than most countries but I am hopeful we will throw our weight around to counter the bs. https://www.chhs.ca.gov/blog/2025/10/17/governor-newsom-announces-affordable-calrx-insulin-11-a-pen-will-soon-be-available-for-purchase/
Seems like something other states should get in on. Now that the program is established seems like it would not be as hard to pay into it and get a share of the product.
But that's socialism! /s
this kind of thing scales well, i see no reason why after california has it set up, other states couldn't get insulin from them, or chip in
I would think Big Pharma will aggressively fight against it.
theres only 3 companies that produce it , Eli Lily, sanofi aventis and novo nordisk, they have fought aggressively through litigation in the past to prevent any insulin generic, or biosimilar to reach the market. they agreed amongst themselves to have whatever the cost they want without competing with each other.
Civica is launching insulin glargine in early 2026 specifically because of that bullshit.
good. generic biosimilars cost like 1/5 of the on-patent thing price
contracting is an interesting choice of word since it could mean decreasing
That's called a homophone.
Well typically it’s said “contracting out” when they mean making contracts
Capitalism is economic terrorism.
One could argue that patents and copyright are anti-capitalist
They are, actually. The point of patents and copyright is not to protect the creator- that's a temporary effect. The point is to release the thing to the public afterwards. The problem is that capitalism corrupts the process and finds ways to make the temporary effects permanent. Disney has succeeded in making copyright last effectively forever.
They are literally monopolies on whatever they concern.
Technically a funnel system for 1%.
yeah. but more importantly your fucked up excuse for democracy is fucked.
plenty of capitalist countries that don't have this problem.
I genuinely think that in some third world countries, as part of the middle class, you can have a better life than in the USA.
Something I've noticed is when untraveled people in the USA try to contextualize themselves with other countries they pick the worst examples they can think of. Favelas in Brazil or slums in South Africa for example. We do this to the point where our entire conception of countries (or in the case of Africa, continents) is the worst imagery we can think of. I think they genuinely don't believe that, for all their troubles India, Brazil, Mexico, Nigeria, etc also have smartphones and big buildings and libraries and universities and laboratories, and educated people living decent lives.
They also can't see how the overcrowded jails full of pretrial prisoners, the barefoot children carrying buckets for water in Appalachia, the rundown schools full of illiterate kids, the impunity of rich private interests, the corrupt sheriffs and judges, and on and on, puts us in the company of the "third world countries". Yes we have nice places too, but SO DO THEY. A broken society in the 21st century isn't people living in mud huts, it's children shitting in the street next to a glass skyscraper with LEED Platinum certification.
And it's not just "overcrowded jails full of pretrial prisoners, the barefoot children carrying buckets for water in Appalachia" but the grad students in LA living out of their cars, or grandpa sleeping on a bus stop, or people in the Rockies surviving off roadkill and forage.
Seattle tent cities/tiny homes make some Favelas look real swanky.
Logically, it's not about how much money you make, it's about purchasing power. It is irrelevant if you earn only $400 a month when you can eat well for $1 and pay $100 for your housing, you have free health care and education. That is the reality in some third world countries.
Third world doesn't mean poor, it just means not aligned with US or Russia
Espousing an old no longer relevant definition to sound smarter and be "right" is peak lemmy/reddit behavior. Third world does mean poor now.
It doesn't. It never did.
It does. Strictly it does. Why do you think china is no longer considered third world?
Strictly, technically every other way China is still third world. This concept of third world being poor seems to have originated from the common charity ads in the 90s and 2000s who loved the phrase, and from the American exceptionalism that thinks everything not American is dirty and poor.
Being poor is the only way a country is third world or not. Being politically related to America is not relevant to the present definition. So no, it is not "technically in every other way". It just is not a third world country, period.
It used to mean that. First World was US aligned (or at least US friendly), Second World was Soviet aligned, Third World was not aligned
Now though, First World means developed nations, Third World means poor nations, Second World has fallen out of use
Only to those ignorant of it's meaning. Developing nations is what people mean. Like people say third world, third to what? What's first and second?
No one really uses that word in its Cold War context anymore. It's the common term for "developing countries" and the like.
People believe that only because they haven't learned what it actually means.
You're right that they either never learned what 1st-2nd-3rd world really means, or they forgot what they were taught in history class. Unfortunately it still is the main term to refer to poor countries even though it's incorrect. Language seems to be biased towards the common meaning over the technically correct meaning.
Spain isn't third world, it already had shown the middle finger to Trump and also has few to do with Rusia. Third world countries don't certainly mean people starving, the people there often have all what they need, but this, you'll see few Ferraries there and chalets with swimming pool. Someone is rich, not necesarly because a lot of money, but because he need only few. We often enter in a rabbit hole of the consumism, spending a lot of money in things we really don't need, we work like a dog to have enough money to pay a journey to Hawaii to recover us from the burnout, which we wouldn't have working less, no needing this journey.
Have you been to Spain? I'm not saying it is not better than where the US is headed to, but it's a "western" country in Europe, with all the issues that come with it. Somewhat social market economy, but still suffering from the usual issues, including people driving Ferraris while others sleep on the street.
Also, at least since Franco I don't think anyone genuinely thinks of Spain as third world.
Well, I'm from Spain, also in Spain there are People with Ferraries (few) and also poor people, but there is nobody without food, because Spain has a strong social system and free healthcare for everyone. Nothing, absolute nothing to do with the US, it's the opposite in almost everything. Luckily Spain has also little dependency on the US or Rusia, so it is also not much affected by Trumps Tariffs or Rusian Gaspolicy. Trump hates Spain.
If you can eat well for $1 then it is definitely a poor country relative to the US. Differences in purchasing power are a direct result of differences in wealth.
I think that the US is a third world country, it's rich but most money is used for weapons and to make richer the billonairs and big corporations, in the social and cultural sphere, it is one of the most backward in the world. Now with Trump the US is turning in a running gag for the most countries. A country where 40 milloncof citizen don't have enough to eat at least 2 times a day, isn't a rich country.
I really should just put a full block on lemmy.ml. Thanks for the reminder!
Usa is the hub of first world. Russia is the second. Thirds is everyone else.
USA is an total dystopic country, any Banana Republic has more culture. US is only powerfull because use all the money for weapons, developed by foreigner scientifics. First world is anything else.
You will say that the US is a first world country, it's better for your health
There's a reason countries like Vietnam are so popular with digital nomads.
My dream would be to get a remote nightshift job and live in a house by the beaches of south Thailand
It's also much harder to become a middle class in those countries.
Not really. Poverty rates are higher, yes, but many middle income third world countries do have sizeable and growing middle classes. They're called developing countries for a reason. The image of war-torn African countries where everyone works in mines isn't really representative.
Naive question from a european: Aren't there companies on the market who can offer a cheaper price and therefore beat greedy competitors?
the problem is that there is natural (as in, unmodified) cheap generic insulin available, it's just that it sucks compared to everything else. you see, insulin is a peptide that is supposed to appear, do some signalling, then disappear and unmodified insulin copies this thing exactly. the problem is, most of the time when peptide is supposed to work as a pharmaceutical, you don't want to do that, you'd like insulin to last longer than usual, which means changes to it that make breakdown slower, or adding something that makes it stick to albumin, which has similar effect because it hides insulin somewhere enzymes can't reach it and also it makes it start acting slower. this means less frequent dosing and less changes in insulin activity over time. there are also other insulins that start acting faster than natural, and this is also due to a couple of modifications in its structure
for another example, ozempic was not the first drug in its class, it's also a modified peptide, and it can be injected s.c. once a week, compared to previous iteration (liraglutide) that requires daily injections. if natural peptide is injected i.m. instead, its halflife is half an hour, and in serum it's only two minutes (it gets released a bit slower than it is metabolized)
manufacturing costs are about the same for any variant, most of it is in purification. patents for a couple of these have expired anyway by now, but if manufacturing is limited then price can be set arbitrarily high (see daraprim)
Oh wow, an actual nuanced response and genuine answer!
Also today I learned!
Responses don’t need to be nuanced to be useful.
Yeah, alright buttnugget.
Alright Caroline
???
Since your comment was entirely superfluous, I just replied in that same spirit.
https://www.youtube.com/watch?v=BxUTu1R5iKY
Costs aren't just research and purification, it's also good manufacturing practice and quality control.
i mean i don't think about it as a separate budget line because if you don't have that you get police raids and investigation instead of normal business, but yea. insulin is purified using HPLC, so at all times you get some of analytical data about fractions you just made, so some of QC, not all, but already something, already happens at this point
my point is that actual manufacturing costs will be low because biotech scalability logic is that you need to make yeast or something that makes peptide you like and then all you need to do is keep bioreactor alive and happy. lots of what is left is in purification
also it's an injectable so it's gonna be kept to some standards that non-injected drugs aren't. whoever comes up with insulin pill will be printing money
thats why the big 3 companies make different version insulin so they are effective at certain times of the day, or when you eat/
there are multiple short-acting and long-acting insulins because you can't patent other people's things, but now it's all off-patent. just take your stainless steel bioreactor and preparative HPLC, cook up a batch, wait ten years for biosimilar approval and you're good to go
because unlike with small molecule drugs, when cooking up generic biopharmaceutical there’s extra approval process that amounts to a tiny clinical trial https://en.wikipedia.org/wiki/Biosimilar this and type of economics of scale that there is with biologicals makes manufacture at large scale way more preferable. these requirements were loosened a bit over time
very interesting!
Correct, but when it's already been established that people will pay those prices, they keep them high. So instead of going from $800 to $5 out of the goodness of their hearts, they go from $800 to $650 (number made up) to get more business but still make massive profits.
You'd THINK capitalism would cause that to happen, wouldn't you?
Doesn't work when people don't get to choose not to take it when it gets too expensive! That thing that capitalists always forget about: necessities.
Every time someone talks about you being supposedly free to choose where to work they should get instant diarrhea. Let alone medicine of course, that's a hard dependence.
Nobody is truly free without proper UBI and free healthcare and good public transport. Only then true freedom can exist.
Amen!
instant diarrhea, haha, but yeah, it carries the point across quite well. some people can't work wherever they want, at whatever job they want, because they have health conditions limiting their range.
Capitalists don't forget. They exploit.
Yes, correction noted
A lot of the benefits people associate with capitalism require a free market. The US problem is that the megacorps have gotten sufficiently powerful to abolish that free market through regularory (and legal) capture, enabling entrenched monopolies.
Look, mate, Intellectual Property Laws are literally the government creating and giving somebody an artificial monopoly on something which would not naturally exist if it wasn't for artificial limitations on "doing the same thing" being forced on everybody thanks to legislation and the coercive powers of the Legal system, and this was purposefully written in Law to do exactly that, so it's not an unexpected legislative side effect.
So anywhere were Intellectual Property legislation can apply the market is not free, on purpose and by policy.
Now, a good argument can be done about how IP law incentivises the creation of things with a high utility value which would otherwise not be created, but that doesn't alter the fact that the whole thing is a giant legislative sledgehammer with massive destructive capability for both the Economy and people's lives, which needs to be handled very carefully in order not to do more harm than good.
As it so happens IP has gone completelly out of control in the US because Corruption there is incredibly high, more some when it comes to the property of ideas since holding a piece of such property can yield billions of dollars in profits - the profits from owning ideas can be far vaster than of merelly owning land - and this shit has been copied around the world by almost as corrupt politicians (for example, the thoroughly corrupt crooks in the EU commission pretty much copy every single "this will make me personally lots of money from thankful corporations" pieces of legislation from the US).
So Copyrights now last an insanelly long period - about 1.5 times the average human lifetime - before things covered by it go into the Public Domain, whilst lots of Patent Offices (most notably the ones in the US and Japan) will just accept patents on everything no matter how obvious without even a proper search for prior art, hence things like the "round corner button" patent that Apple has as well as countless business patents for "solutions" which are obvious to any domain specialist (many such patents literaly the product of paying a domain expert for an hour of their time by a patent troll to just "think up a solution for this" as no actual implementation is needed to get a patent, just the idea of how it could be done).
All this to say that this fucked up situation of insane government-given monopolies all over the place for shit that's obvious to domain experts or derivative (a common trick in patents for medicine is to just do a small tweak in the formulation to get another 25 years of patent protection on pretty much the same thing) was created ON PURPOSE by the very politicians who claim to want a Free Market.
The entire thing should be reviewed and ajusted in exactly the opposite direction it is going (so we should have shorter protection periods, no "ideas only" patents, proper prior art searches rather than relying on expensive court cases to nullify patents on things somebody else already did or which are common practice in that industry, no business patents, properly funded Patent Offices, no transnational recognition of patents - so that countries *cough* Japan *cough* can't just use their Patent Office as some sort of commercial weapon to benefit their local companies in other markets - and so on) but given that Intellectual Property is an area worth trillions (and, remember, it's entirelly artificial, so without that legislation such property would be worth nothing at all) and politicians are incredibly corrupt nowadays, this shit is getting worse rather than better (and, IMHO, severely slowing down the speed of progress in the current Era versus a Free Ideas system)
Sectors like pharma require enormous R&D budgets. If you have a free market with many companies, each company will have only a tiny marketshare, and therefore only a tiny budget. So you can't do without the megacorps. The solution is for the megacorps to be run by the government / non-profits / trusts, or, if that is not possible, for prices to be fixed by an independent regulatory body.
What USA is experiencing is feral Capitalism.
Crony capitalism
That's certainly how capitalism is marketed, isn't it?
Yup, but their products don't work as well, don't work for everyone, or have other downsides. Banting's original insulin would be dirt cheap today, but it's shit compared to what we have now, so the best products on the market today charge a premium for either efficacy or convenience.
oh, it gets better. Baby born with Spinal and Muscle Atrophy? There is a cure! $2,500,000!
They hold lotteries for doses, a few babies win, most babies die.
We all do. Luckily most of us only have to live with the fallout and not actually have to be there.
Americans suffer from Stockholm syndrome
In genuinely think that more countries should allow refugee status and (economical) protection to people from poverty stricken countries like the US.
Reminder that the term Stockholm Syndrome was coined to blame victims for being rightly more afraid of the police than their captors:
Otherwise, we probably agree that AmeriKKKans are a feckless, servile people.
Mod note: Do not make personal attacks towards this user, lest I have to slap more knuckles with a ruler. You can engage with the critique respectfully, or it's 📏 time.
Wow, lots of 📏 around here.
?
My comment was in response to a comment about AmeriKKKans having "Stockholm Syndrome", which as it turns out is not a real or valuable diagnosis. However, I do not disagree with the implied critique of AmeriKKKan people as being feckless and servile people.
You lost me with thebrepeated "amerikkkan" thing.
A: It completely undercuts the seriousness of your comment and makes the whole thing come off as a tirade by an edgy teenager.
B: Jokes don't get funnier every time you repeat them, it was mid the first time and eye roll worthy by the 3rd.
I agree with your points, just sucks that you chose to present it in such a juvenile way.
So you disagree with the tone and not what I'm saying? Because if so, that sounds like a "you" problem, i.e. you're more interested in the tone of a message than its content.
It's not a joke and it's not supposed to be funny. I genuinely hate the USA and everything it stands for.
Man you really need to work on your communication if you ever want anyone to listen to you.
This is very much so a you problem because you're not going to get far acting like this to people who agree with you.
No I'm pretty sure you're a liberal, right? We probably do not agree almost at all. See this video for more information.
i dont think STOckholm syndrome applies to a large population. brainwashing, propagandization is what its called.
Nils Bejerot was a total hack. He tried to ban comic books, and later transcribed that same energy in a war on drugs that has resulted in some of the worst health outcomes for drug users in Europe. Unfortunately his ability to be confidently incorrect swayed a lot of gullible rubes, and his legacy still casts a shadow over Sweden to this day.
AmeriKKKa is a settler-colonialist project, and the entity and its defenders deserve zero respect. I mentioned AmeriKKKans because the person I replied to used Stockholm Syndrome to critique AmeriKKKans on a post critiquing the AmeriKKKan healthcare system, so critiquing AmeriKKKa is relevant here. And I don't like spelling AmeriKKKa as part of USA correctly because (1) places like Central America and South America should be distinguished from the United States of AmeriKKKa, and (2) it offends the people who need to be offended, i.e. people who still feel affinity for the AmeriKKKan project and people who tone-police others who are just brutally honest in speaking their minds.
You are literally posting from an anarchist Lemmy instance, why TF is this controversial to you?
Yeah I hope I get the mental help I obviously need...oh no wait I'm in the US so no I won't
Fine, just do Ctrl+F, replace each instance of AmeriKKKa with {insert preferred term for the United States}, and move on with your life. Like I'm not even trying to get you to say it, I'm just saying it. It's almost like you have a problem with what I'm saying and not just how I'm saying it...
Soo why sell the patent for $1 and have it be potentially exploited when you could hold onto it and licence use for free?
IIRC the insulin being sold now is manufactured differently and the patents are completely different anyway
But overall your point is good
It is different, but it's still incredibly cheap to make, $4 a vial, so it costing in the hundreds is just antihuman...
It's not anti human, the rest of us get it just fine. It's specifically anti-american
This is a great way of phrasing things.
Services that are necessary for life (like healthcare)...if other countries have figured out how to make it affordable/free (at point of use), any person or industry that tries to extract profit out of it is literally anti-American.
Bingo. It's extortion and if the asshat in charge gave any kind of a real fuck about cheap medicine it should've been a day 1 fix.
Absolutely. I'm just saying that the original guy selling the patent isn't the reason that corporations can gouge Americans for insulin now.
The insulin produced now has benefited from advances in technology just like most things. The fast acting insulin is predictable and works in 45 minutes to an hour and a half. The original insulin took hours and wasn't nearly as predictable or stable. Testing/monitoring technology has seen even more significant advances.
I owe Banting and his colleagues my life, but it is different. That's not to say that the continued well being of the public should be profitable and exclusive.
I mean insulin is about 10x more expensive in the USA compared to other Western countries. It's cheaper still in lower income countries. Many European countries also have a price ceiling for medication, so your monthly cost for life-saving drugs is capped.
I don't know exactly why a manufacturer doesn't set up production for much cheaper generics in the USA, but for whatever reason Americans are getting price gouged like Satan doesn't believe in tomorrow.
Whatever reason? Simple reason: legal to maximize profits over people's misfortunes.
To be fair, most Americans agree with the capitalist first approach right up until it affects them individually. If they were willing to help each other instead of believing that anyone other than themself is a freeloader and lazy, they would have the support that other countries take for granted.
They wouldn't be 'freedom loving' or 'American' if they actually gave a shit about other people.
It was sold to a Canadian public university to manage the patent for public good.
They have, everywhere else in the world basically, insulin costs pennies.
In America, they have been able to patent certain formulations and delivery methods, and they keep making marginal modifications to string the patents out to keep Americans locked in to absurd insulin prices.
Was that the answer you thought it was going to be?
Welcome to USA, I guess.
In other countries, you could probably completely fill a fridge with insulin for $800.
If you need a lot of different prescribed drugs then £114.50/year to cover every prescription you have is an option here. Otherwise £9.90 each.
https://worldpopulationreview.com/country-rankings/cost-of-insulin-by-country
I can confirm, as a insured I am paying $0.00 for Insulin in Macedonia. Now I am receiving 6 Novo Nordisk Tresiba pens per month. How much is that in US?
I couldn't find the answer easily myself and ended up asking AI, so take this with a significant grain of salt, but supposedly a 3mL pen would be around $145 without insurance. If anyone can find a better source, I'd be all ears.
Is it free in grey countries?
Either that, or maybe they don't have diabetes there. (Lol joking)
1/5th cost just by driving to Canada.
Something in american.
It's 10¢ in developed countries like Georgia
https://gpc.ge/en/details/ptient-care-items/disposable-materials/syringe-insul-1ml-u-100-g-29-1?product=24643
And let's be clear, we're talking about the European OG Georgia, not the US state.
Isn't that where Palin saw the Russians?
Russians with almost free insulin, friend
They sold the patent to the University of Toronto, so they didn't exactly sell it to a for-profit patent troll.
But also, that was in 1923, so the patent has long since expired.
They also don't make insulin the way that he did back then. Not justifying the price hike cause the way its made now is way cheaper than it was with the old method (which was basically grinding up animal parts to extract insulin). These fucks are just profiting off of the suffering of Americans who have literally no choice but to use their drug.
https://youtu.be/naqbi_qVoVY
I never heard of disclaiming a patent until just now. Maybe he didn't know about or it didn't exiat in the 1920's
Remember, the 1920s is long ago. Giving the patent to the equivalent of a non-profit organisation was probably better than disclaiming it, since it's easier to have one large, well-known entity that will fight off people trying to re-patent it than to disclaim it and hope that no patent clerk ever lets a fraudulent re-patent go through.
In 1920 you couldn't just google for prior art when fighting a fraudulent patent.
Nowadays you just google for other patents and done. But back then, I guess that searching for prior art was quite a lot more difficult. Gifting the patent to an university so that they defend open access to the patent sounds like a more reliable plan.
I mean, even nowadays patents are greenlit my patent offices even though there's clear prior art (Nintendo's recent patent for catching monsters in a ball in a game comes to mind, which Nintendo would have to have patented before publishing their first game with that mechanic around 30 years ago), and even today it's really difficult and expensive to get such a clear nonsense patent invalidated.
So difficult that e.g. Palworld opted to change the mechanic instead of fighting the patent.
So I do understand why someone would instead gift the patent to an university under the condition that they keep access to it open, especially 100 years ago.
The difference is that in the case of transferring the patent to the university, there's a legal department at the ready to defend the patent. The same is not the case for a disclaimed patent.
Yes they will absolutely fuck you on it IF they even allow it at all.
You know, in the spirit of "free markets" and all that bull shit.
I believe there are some restrictions on mailing insulin across the border due to regulations and customs laws. However, there might be ways around it if you're willing to do a little research and possibly pay extra fees.
What website would we mail order it from?
couple of reddit threads suggest that this is something you can do, but you have to be evasive around american border guard later if you go in person
people have been crossing to canada for cheap insulin drugs, the same one made by the trioply insulin companies via driving. other healthcare options, like dental work or medical procedures, they will be seeking places like thailand, mexico, india(the cities that cater to medical tourism)
These god damn foreigners crossing the border to leech of developed countries. They really need to put that wall up.
Fuck.
Invented by a Canadian, exploited by an American.
https://fourthievesvinegar.org/
It is not a solution, but maybe an alternative to death…
fyi this fella has no training in chemistry or medicine and is just some random ass programmer with severe case of "saving the world from my homelab" symdrome
It is widely available, just not in the US
US Healthcare = pay or die
Oh, it's not that good.
It's "Pay until you run out of money and can no longer take on more debt. Then die."
Let yourself be captured by the ICE, so they expel you for free to a civilised country.
Civilized countries don't run camps for ICE.
US hEAlthcare.
Pay a monthly subscription fee, and additional microtransactions every time you get rejected.
You forgot the middle step, vote for republicans to perpetutate the situation, and then die.
It's yet another thing to force the riff-raff to work any job for any pay.
Can't have people refusing to do disgusting or even life-long disabling jobs for peanuts.
See also "housing costs".
https://worldpopulationreview.com/country-rankings/cost-of-insulin-by-country
At least you can buy a human for only $85.21!
Lots of missing data in there, but gotta love Turkey's $2.56.
Were I am, you just get Insulin for free with a prescription from you Family Doctor, because we have a National Health Service.
Even without said prescription, it's only €70.
Americans are being thoroughly screwed, and it's very much on purpose thanks to the way laws and regulations around Healthcare were designed in the US (and, at the risk attractint the crowd throwing "bothsideism" slogans around to defend "their" "tribe", this is due to the actions of both US major parties) since in a real Free Market, Insuline over there should cost around the same as it costs over here without a prescription, not 10x more - without artificial market barriers there would be investors literally flying planeloads of the thing from Europe to US to make a killing out of buying it cheaply over here and selling it for "merelly" twice as much over there.
I summon, Luigi!
My name's not Luigi
What are you summoning
grunts Damn thing isn’t working.
In Canada it is still considered expensive, but not even close to $800/month. It's only considered expensive because most shit like that is free or a very nominal fee, but repeated need is what it is.
Shoutout to the uninsured cost of the medication I need to live
(90 tablets)
Does anyone really need to live? What you need is to be producing value for your company!
/S
Also I just remembered, I used to have United Healthcare and they didn't cover this medicine so I had to switch. Had to pay ~$300 for that refill (i think it was fewer tablets and 75mg that time). $40 on my current insurance.
Anyway I'm a big Luigi fan
yuck, did you use optum health? they are owned BY UHG.
Using Aetna currently. That is good to know though
A patient cured, a customer lost. A dead customer, just a cost of business.
^ Say "for profit medicine" (oxymoron btw), behind closed doors.
How is it even possible to afford $800 for insulin? It boggles the mind
Is there any reason a diabetic has to get the newer patented formulas instead of the old one that the pic talks about which is regularly sold for around $25 a vial in the US without insurance?
I know the new stuff works faster and you don't have to worry about your diet as much so I'm sure it's much easier, but why would you have to die instead of just managing your diet and using the $25 stuff for a month in this emergency situation?
Don't get me wrong all medicine should be free and stuff but like, why die instead of switching to the cheap stuff and dietary management for a month?
Insulin is not permanently shelf stable, and will still expire in the fridge.
Diabetics usually start with a long-acting insulin to keep blood sugar from naturally rising plus a fast-acting insulin for corrections and to compensate for food.
The old style of just giving 2 long-acting shots of mixed insulin is mostly obsolete, except for legacy patients, some pregnant patients, and other special cases I can only theorize.
A good number of diabetics only use fast acting insulin in a pump, receiving microdoses every minute.
To switch brands of insulin, much less therapies in any circumstance requires a doctor's visit.
With all that said, the insurance company will often replace a medication in the event of an accident, typically only once a year.
Without that, a patient might be able to find a charity they will assist them.
You also may be able to travel to the next state over where the cost of insulin is regulated.
Failing all other options, it is better to check yourself in to the hospital as your sugar begins to rise and tell them that you cannot control your blood sugar.
I don't think I ever had insurance in the US where checking into the hospital for any amount of time would cost less than $800 out of pocket.
Unless I had already reached my annual deductible, that is.
"Hey good news! After about 35% of your annual income is spent on medical bills on top of your triple digit monthly premiums... That health insurance starts to kick in!"
(Until it resets at the end of the year. Teehee!)
The deductible system is ridiculous.
It truly is amazing how an entire industry makes billions by literally avoiding delivering the most basic service it's paid for at every possible turn.
This is not even good capitalism. Capitalism was intended to provide efficient solutions through competition. This is an oligopol secured by generous bribes
The extra ridiculous thing is how they deny services that a doctor says are medically necessary… and not even in a reasonable way, in an abusive way. Like the system that automatically denies 60,000 things an hour or whatever, and count on people wasting tons of time to challenge it. Or when they have an ophthalmologist review your kidney disease and say that some treatment isn’t warranted. And that’s even after you’ve paid your stupid deductible costs for the year.
It's no longer about saving money at that point.
Ah well that's good, at least there appears to be some options.
I've heard of clandestine labs making patented insulin and selling it cheap too, and I'm all for a good grey market.
Not sure about that, and not sure if I could trust that.
Another option is to have the doctor prescribe insulin pens or another brand of the same kind of insulin. It's technically a different prescription and the insurance company usually covers it.
The subs would be R and NPH, not the old mixed formulas like 70/30.
People respond wildly differently to different types of insulin and it isn't just a matter of switching and watching your diet. Too much and too little insulin can be deadly and it makes you feel like absolute shit.
Ah, so you'd need to know your dosage for that type beforehand, and if you didn't know it you can't just wing it. Still though, might be beneficial to know that for emergencies like this because it sounds preferable to certain death.
There should be a little chart your doc gives you at diagnosis (or something, spitballing here) that lays out the dosages you'd need for X, Y, and Z brands so that if say you use X and they're out (or your kid freezes it or something) you can just consult the dosage chart and get Y for now.
A unit is a unit, so the dosages are the same. What varies is onset curve and length of action, so timing.
I don't think it's a thing because even the same insulin analogue from different manufacturer can have different dosing
The old formulas you can buy OTC for $25 are more inconvenient to use, but will indeed keep you from dying. The main difference between the R insulin and Novolog/Humalog are how quickly they act. Novolog starts lowering your glucose in about 60 minutes while the R takes 2 hours. Dietary management is not related to which insulin you’re using, at least for type 1. The long acting substitute, NPH, is a lot more difficult to use than Lantus though. It still works. I ran out of good insulin on a trip last year and had to sub the R and NPH and did have some issues with hypoglycemia. I’m more qualified to swap them on my own than many people though (lots of people are not informed enough to change their dosage without professional medical advice).
So yes, the claim that OOP’s only alternative to paying $800 was to die is not true.
We should be thankful for those of us not born in a third world country like the USA. 😌🙏
No no this is a "there are starving kids in America" thing; for a good chunk of the third world this shit would be literally unthinkable.
as an American I'm offended. how dare you compare third world countries to the US.
they may be small and unsuccessful but damn it they're trying.
Yeah, just dismantle the state and give it to private companies... What could go wrong?
I really don't get it. If it was in the freezer, why will it be damaged when put back again? Is it that once defreezed some reaction goes on and shouldn't be stopped? I really don't get it. Would it be better to keep it outside the freezer once it warm up?
It degrades from the freezing process and then dosage becomes unpredictable and thus dangerous. If you have insulin it's got big words on it saying don't.
Heres the side of some humalog:
DO NOT FREEZE. Store refrigerated at 36°F to 46°F [2°C to 8°C] until time of use. Store in-use vials refrigerated at 36°F to 46°F [2° C to 8°C]. If refrigeration is not possible, store at room temperature (up to 86°F [30°C]). Protect from direct heat and light.
I’m sure an experienced medic in an emergency could work with it somehow, but for the rest of us living in civilization, insulin that has been outside their recommended temperature range is very dangerous.
Long-acting insulin has crystals that dissolve at body temperature over time, hence it can gradually release insulin over hours. If you break or dissolve those crystals by freezing/thawing/overwarming, the best scenario would be that it became fast-acting insulin, and it would crash your glucose instantly on injection of your usual dose. The worst scenario is that it no longer acts like insulin.
Other way around. The removal of the prolonged release is what would kill you right away. Hypoglycaemia kills WAY faster than hyperglycaemia. Like - one takes minutes, the other one hours to days).
I thought “crash your glucose instantly” would be understood as hypoglycemia, but English is not my native language.
I think they’re saying that your proposed best case causes possible instant death, whereas the proposed worst case would take days to kill you.
Neither it is mine,so maybe we both missunderstood each other. No hard feelings.
But "worst" is generally,well the maximum.
Freezing temps breaks down insulin and causes it to lose efficacy which less efficacy is something you don't want with something that keeps you alive
Methinks you read it wrong friend; it was stored in the fridge originally
It was in the fridge, then put in the freezer.
It apparently loses effectiveness when subjected to extreme temps, but that loss depends on length of exposure. [Source]
it might just be in glass vial and freezing broke it
rea bra
Sold the patent for $1, that's so Canadian.
For Australian diabetes patients the insulin Fiasp is $31.60 on the PBS, but Americans pay $930, while the medication Jardiance is $619 to $698 in the US compared to again $31.60 for the 220,000 Australians who access it. (I'm on Jardiance)
'Murica, fuck yeahhhh!
:::spoiler Needs text alternative. Images of text break much that text alternatives do not. Losses due to image of text lacking alternative such as link:
Contrary to age & humble appearance, text is an advanced technology that provides all these capabilities absent from images. ::: Did they try looking for discounts from patient assistance programs from the manufacturer? They'll reduce the cost to $35.
Manufacturers try to shakedown insurance companies for obscene pay without affecting the amount individuals pay, so they offer those programs directly to individuals. Not saying this good, just how the system works.
i think thats recent, because eli lily, novo nordisk, and sanofi aventis originally had a TRIOPLY on insulin, they got scared because California was planning to making thier own version lowering the cost. originally they dint do that, and vials were hundreds of dollars.
biologic medication does something similar, like a coupon for thier EXPENSIVE medication, even with it, the cost is still pretty high.
When you kill the wealthy and their enforcers, you should be shouting "blood for blood".
No. They kill us. They murder people. Make it clear why this is happening, why any negotiation starts with every billionaire shot in the gut and left to bleed out, as a compromise.
Theyll do that anyway..
my plan is to die in the water wars in 3-5 years.
You seem to think any of those people are competent. They generally are not. The fear, the obedience, is why they can control hundreds of millions with a few thousand thugs. Fuck your obedience.
I was more planning to get shot in the head as a bystander somewhere, but maybe nestle will try to recruit me or something, idk.
If I'm remembering the original sysntesis for insulin used dogs, and it was harvest from them after being killed. It's unjust that insulin is so expensive, but also modern production methods are not the problem here. It's greed.
Stanford has managed to cure type 1 diabetes in mice. Lets see if big pharma lets that get anywhere.
90% of drug candidates fail in clinical trials
There's no business in curing diseases. The whole pharma is mostly a "subscription" model.
do people just not have credit cards?