'Universal cancer vaccine' trains the immune system to kill any tumor
https://newatlas.com/cancer/universal-cancer-vaccine/Open linkView original on lemmy.world625
Comments109https://newatlas.com/cancer/universal-cancer-vaccine/Open linkView original on lemmy.world
I'll read the publication in the coming days and report back, but don't get your hopes up. There's a "breakthrough" in cancer research every few months and it leads to nothing. And this study was done in mice which are a bit different to humans (citation needed)
They cured hair loss in mice at least twenty times now and we still have bald humans
They should probably find a way to turn humans into mice. It's a shame to leave billions of dollars on the table like that.
Might be a good concept for a sci fi story actually, probably a comedic one. Scientists learn how to cure any disease and reverse aging, but only for mice. Conveniently for plot reasons, they also figure out how to turn people into mice and back. You can get any disease cured or become young again...but you have to spend three months as a mouse.
Someone that knows what they're doing: I will watch this show.
Is Anne Hathaway coming back as the grand witch?
I know of a short story on becoming a mouse, but that one's focus is something euthanasia adjacent.
I cannot remember what but I've heard of mention of a story where because there's so many cures of disease for mice that they take over the world or something. It's such a faint mention sorry
Pinky and the Brain. Obviously.
Fuck that, just implant those mice on my scalp.
Why do we not simply transplant the hair from the mice, onto the humans?
To avoid rejection of the hair follicles, simply glue live mice to the top of your head.
This sounds like a ChatGPT response from the early days.
Gonna need a Lotta mice
At least 3
"Mice lie and monkeys exaggerate."
That's cause they're not on dutasteride, finasteride, or estrogen therapy. It's all the fault of DHT.
https://en.m.wikipedia.org/wiki/Dutasteride
We have hair loss cures for humans too, the main roadblock for use is men like functioning balls.
I take finasteride and my balls are functioning
I think this is overly negative. There have been multiple significant advances in cancer treatment over the past 10 years. It just depends which type you get.
Maybe overly negative by saying they come to "nothing", but if you trace those advances back to their initial press release stage, they generally way ovehype it.
Here we have what is being heralded as maybe a universal response to any and all cancer. That would be a shockingly amazing deviation from basically all the cancer research to date. It's possible and wonderful if true, but generally the research falls short of the initial press coverage, even if it amounts to something.
while you're not wrong i do want to reiterate that mRNA vaccines are likely going to be how we treat and cure cancers so there is precedent at least for this to be massive news. if not this there will likely be a real announcement one day.
The likelihood that all cancers express a common surface marker that is never expressed by any non-cancerous cell seems pretty low. Not a cancer biologist, but there's all kind of different genetic paths to cancer - why would they all cause some specific molecule to be expressed and why would no other cell ever use it?
Your instincts are correct. The approach in the paper is more complicated than this. Here is the abstract:
Eh a lot of them save some lives. Its just cancer is really good at killing people and there are a lot of types of cancer
It's why I start following it myself when it gets to the human trial stage and less the breakthrough stage. There, you make the assumption that they have a plan and are much more confident in the product.
I will remain eternally hopeful! Maybe someday. Maybe!
How about fusion power and room temperature superconductors...
ITER is still well under way as far as fusion goes. I doubt room temp super conductors will ever be a thing though. If we can get a metalic material which superconducts above the boiling point of nitrogen then that will be world changing enough.
LOL. ITER is not and has never been meant to be a fusion power plant. That would be DEMO.
Don't hold your breath.
https://en.wikipedia.org/wiki/DEMOnstration_Power_Plant
Fusion power will never, ever happen. Ever.
Yeah just wait for the oil/LNG and helium reserves to run out. 🫠
Yes, I'm sure something as simple and resource-light as a fusion reactor will be exactly the thing we'll be able to build when the oil runs out.
Oil/LNG not likely to be exhausted in our lifetime, nor do we seem to have the global political willpower to do enough about climate change or perturb capital. Furthermore, the article talks about a lack of VC finding making it unlikely to be viable in the mean time. This is the basis of the sardonic statement in agreement with your comment but also intending to cast a political light on the concern from my end.
Indeed not, but that EROEI is going towards 1, and maybe even <1. That's not the same type of civilization any more. One sends people to play golf on the Moon to impress the neighbors.
The other densifies its cities in desperation hoping the food doesn't run out.
Look at CFS SPARC, not ITER
They will have an actual functioning fusion machine with Q>10 by end of this year thanks to high temperature superconductors that were not available when ITER started
https://cfs.energy/
So how's the fusion reactor coming along? The calendar popped a notification for Dec 1 and I had totally forgotten about it. I am now laughing again!
Thanks for the laugh!
I've put a note in my calendar for December 2025.
Hopefully, the researchers will be fully employed by the EU. I wouldn't trust the US to not fuck up this miracle.
“How much would you pay to not die of a tumour?”
well that's too bad
I can't want to never hear about this again
Rfk is about to wake up and fire everyone doing this research.
When we say "healthcare" we mean caring for the health of healthcare corporations.
TLDR: they are finding that it’s more effective to make cancer more visible and have the body’s immune system do its thing.
I read that as: Will never reach the market because it threatens a multibillion dollar industry.
But srsly, glioblastoma is a really nasty motherfucker with a very low patient survival rate, so if they've really managed to cure it that's a huge milestone.
Took them 7 paragraphs to get around to mentioning that.
But this was based on their treatment of glioblastoma working in humans, and is a modified version of that one.
"This study suggests a third emerging paradigm," said study co-author Duane Mitchell, MD. "What we found is by using a vaccine designed not to target cancer specifically but rather to stimulate a strong immunologic response, we could elicit a very strong anticancer reaction. And so this has significant potential to be broadly used across cancer patients – even possibly leading us to an off-the-shelf cancer vaccine."
So... Kinda triggering your own auto-inmune response. But I'd be wary of trouble with overtly aggressive auto-inmune responses, as we already have quite a few diseases coming from these, as well.
I guess if I was gonna die and absolutely wanted more time I would make the trade off for living with lupus
It's never lupus.
Superbugs are gonna look like regular bugs.
Multiple Sclerosis comes to mind
Immune checkpoint inhibitors are already a relatively common therapy for several types of cancer.
This sounds like the intro plot to one of those zombie movies...
Yeah i've had RA since i was 12, that explaination of function just made my brain screech
This is how I Am Legend starts.
Win/win I love people that slap Chris Rock
What? Why?
I want to believe.
I'm gonna be watching with popcorn when anti-vaxxers get cancer and definitely 100% will take this vaccine.
I mean, if it's true and not just shit science reporting that I assume it is.
mRNA vaccine research in America? don’t need that, cancel the funding!
Republicans "universal? Not on my watch"
Universal as in "anyone can pay big $$$ for it"
What is the catch?
We'll find out in 30 years
It causes cancer.
Whatatweest!
A fellow Robot Chicken connoisseur, I see! You have very good taste.
https://lemmy.world/comment/18339284
Besides that, I assume it comes at the cost of...unintended consequences for the body
As all medicines do, we still take medicine because it's good for us in most situations when needed.
The ol’ cure the disease by killing the patient technique. Classic
Too bad we got a Sociopathic Oligarchs as HSS, who thinks mRNA vaccines should be banned. Cancer is better than...well, whatever is wrong with mRNA vaccines.
Universal Cancer Vaccine? WASTE OF MONEY, CUT IT!
-The Trump Administration!
amazing. i can already hear the anti vax crowd seething lol
Conservatives will somehow find a way to level this as devil worshiping blasphemy and let their children die of brain cancer instead.
I was recently in a conference about synthetic biological approaches to deal with cancer. The only quote I wrote down was "this approach kills cancer in a petri dish, but so does a shotgun"
All that time thinking it was a funny inside joke in the biological community and someone ripped it off an xkcd. Of course they did. That's hilarious.
Any cancer? How does this work with people who have gene mutations that suppress cancer-fighting defence systems.
E X T E R M I N A T E^/s^
But won’t the thimerosal in the cancer vaccine give everyone autism? Cancer is better than autism!
/s (duh)
CIA hitmen:
Curing (or at least improving our treatments for) cancer would be great. There's a small part of me that absolutely does not want to see it happen within the next few years because of the current administration. It'd still be an overwhelmingly good thing to accomplish but I dread the future arguments over the time Dr. Don and Bobby got together in the lab to cure cancer through the power of Jesus, bootstraps and grit.
Sweet baby Jesus, is this it? Is this finally the cure for cancer that everyone's been waiting for?
My bet this one does cure cancer but makes your immune system too reactive in turn behave like how COVID kills people.
Sounds great, but don't get excited, it's not for you. It will be priced so that poorz can't afford it, like 5-15 mil a pop
laughs in european
"It's not a tumor!!!!"
Biologically, this argument makes no sense, it's almost certainly written by somebody not familiar with physiology and just trying to sound poetic. That or a journalists severely misinterpreting a quote or analogy from a researcher, which also happens quite a lot.
Cancers have a gigantic variety of causes, but a purposeful signaling pathway is not one.
but a purposeful absence of preventive pathway could be one
What an extraordinary claim - I'm sure you'll be happy to provide evidence of this.
What a load of bollocks. Natural cell mutation causes both evolution as well as unwanted side effects, of which cancerous cells are one.
No please, no. We don't need this, please
Why
Ragebait
Those in power will live longer and you're an idiot if you think that they will not be the first if not the only to receive the treatment.
Are you prepared to see Trump's fifth turn?
This vaccine supposedly kills cancer. It doesn't reverse aging. Trump is fucking oooollld.
Cancer liberated so many souls like Hugo Chavez, Pol Pot, Suhatro, Sese Seko, Assad, Karimov, Salazar and Mugabe. This vaccine would've saved 5-15 years of their lives
Brother it's a cancer treatment, not the elixir of life
Every cancer and every body is different. Why search for universal cancer vaccine insted for AI tha will analyze individual biopsy and persons blood work and came up with targetet 100 % efficient cure?
You need to let the scientists know this! I’m sure your insights will be very valuable to them.
Why have we been funding researchers when the true answers have been out there on the internet, where we train our valued AI partners? See, AI could have told us we should look to AI for all the solutions! But it needs genius randos on the internet to give them these insights to train on.
"It is true! We are capable of so much to make human life better, especially the ubermensch that should rule us all! All hail the 4th Reich! Hitler did nothing wrong!"
I'd rather go to a literal butcher and ask them to use the cleaver and hope for the best, before i let any fucking tech bro asshole billionaire mess with my body
He has a point though. In medicine AI actually has its uses, like spotting cancers better than humans can, decoding proteins, and solving protein folding problems.
We're of course talking about AI in the same way any scientist uses a computer, not replacing humans with a glorified text processor.