Spyke

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20 and don't know how to enjoy life anymore — is that normal?

As someone who knows gambling addicts, that's not a good pattern, and the bad moods get worse when luck turns against them, and get inflicted on people around them.

Do something with other people that's less transactional: A group activity where you're playing or working together. Volunteering, games, sports, hiking, whatever.

At 20, you should be out there finding your tribe to hang out with in person and support each other.

You'll need it then, and it'll be the base for even more mutual assistance in the decades to come.

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Not boring hobby recommendations?

If you live in a city with a parks and recreation department, check out their website for classes and activities.

If it's a sport that requires equipment, such as racquets or bats, loaners are usually available from the department or other participants.

You really won't know what your mind and your body enjoys until you actually try it, so just YOLO random activities, but keep it safe of course. Avoid stuff like highrise roof edge parkour, and you'll be okay.

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Not boring hobby recommendations?

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Also, I hate to say this, but you will likely enjoy something that one of your parents enjoys.

Obviously stay away from genetically disposed addictions like heavy drinking or gambling, but doing the positive hobbies that one or both of your parents enjoy can let you interact with and understand your parents, which is a good thing now and later in life.

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2026-08-25 #2

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More specifically the lyrics from the first verse:

[Verse 1]
Grab your coat, grab your hat, baby
Leave your worries on the doorstep
Just direct your feet
On the sunny side of the street

[Verse 2]
Can't you hear that pitter-pat
The happy tune is your step
Life can be so sweet
On the sunny side of the street

[Bridge]
I used to walk in the shade
With those blues on parade, oh
But I'm not afraid, baby
My rover crossed over, yes

[Verse 3]
If I never have a cent
I'll be rich as Rockefeller, yes
Gold dust at my feet
On the sunny side of the street

science

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FDA clears blood test to aid evaluation for Alzheimer's disease

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There has been no correlation between amyloid and AD since 2008. The rest was all faked.

That's a huge exaggeration of what the article you linked to says https://www.science.org/content/blog-post/faked-beta-amyloid-data-what-does-it-mean

The faked line of research was regarding Lesne's line of papers on a specific amyloid beta protein configuration AB*56

Proteins can be folded in any number of shapes, any of which can have different effects.

The OP's article states:

The blood test uses high-resolution mass spectrometry to measure the ratio of levels of amyloid (Aβ42 and 40) and two forms of tau protein (p-tau217 and total tau217) in the blood. These biomarkers are associated with amyloid pathology, a characteristic feature of Alzheimer’s disease.

As a layman, I see there's a difference between AB 42/40 and AB 56

movies

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Abandoned LA-area (Hawthorne Plaza Mall) featured in 'The Fast and the Furious' 'Gone Girl' 'Minority Report' movies 'Westworld' TV being demolished

From https://en.wikipedia.org/wiki/Hawthorne_Plaza

The abandoned mall has also been used to film numerous movies, TV shows, and music videos such as Evolution (2001), Minority Report (2002), The Green Hornet (2006), The Fast and the Furious: Tokyo Drift (2006), Teen Wolf (2011), Agents of S.H.I.E.L.D. (2013), Beyoncé's "Superpower" (2013), Gone Girl (2014), Lindsey Stirling's "Heist" (2014), David Guetta's "Bang My Head" (2014), Rush Hour (2016), Colony (2016), Westworld (2016), Taylor Swift's "...Ready for It?" (2017), Chris Brown's "Party" (2017), Travis Scott's Astroworld trailer (2018), Drake's "Nice For What" (2018), and Tenet (2020).[18]