I'll preface this by saying I am 100% not aware of every game in existence, but:

What happened to all the good games with a focus on destruction physics?

Red Faction: Guerrilla was one of my favorite games ever. It had its buggy moments, but overall its destruction physics system was fun and satisfying.

Then Red Faction: Armageddon was so terrible it killed the entire studio (that's probably not exactly what happened but I'm going with it), so now Red Faction is in some weird legal limbo or owned by a company with no plans for it or something like that.

The next choice seems to be Just Cause. The cables in Just Cause are great fun, but the structures all feel like they're made of cardboard and mostly are not destructible. Not very satisfying and not very fun long-term.

The best option I've played for current-or-previous-gen (yeah sorry still a console peasant, working on that) was Battlefield 6, which does destruction very well but it's hardly the main focus of the game like it was for RF:G.

So... what happened to good destruction-physics focused games? Are there any out there that I don't know about?

cross-posted from: https://lemmy.world/post/46674861

Greetings friends, and welcome to c/mdma!

This community has been shutdown / closed to new posts for 3 years for unclear reasons. It's now open to the public again!

c/mdma is now part of the c/drugs network of communities. c/drugs serves as the central Hub, branching off into more substance-specific discussions from there.

This also includes the establishment of some basic rules for this community:

Rules

(These rules apply across all communities in the c/Drugs network.)

No Sourcing - Do not request sources of any drugs at any time. This includes unregulated research chemicals. Any attempts, including "hit me up in DMs" type of requests, will result in a ban. This rule is necessary to keep this community open.

Harm Reduction - Do not recommend inherently dangerous doses or combinations of substances, or otherwise encourage behavior more risky than drug use already is by default. Clear attempts at causing intentional harm will result in a ban.

Avoid Dangerous Recommendations - Avoid recommending substances that have a reasonable chance of causing considerable harm to the user. For example, DPH, inhalants, or opioids. This rule is necessary to conform with Lemmy.World's Terms of Service. Posts violating this rule will be removed.

No Minors - Users under 18 years old are not permitted to use this community.

☺c/MDMA Rules☺

• Keep It Friendly - Be kind to your fellow humans. Disagreements, even impassioned ones, are fine. If you bring it down to the level of personal insults or excessive hostility, your posts may be removed. You may be banned in especially severe instances such as racism, sexism, Nazism, Zionism, etc.

Greetings friends, and welcome to c/mdma!

This community has been shutdown / closed to new posts for 3 years for unclear reasons. It's now open to the public again!

c/mdma is now part of the c/drugs network of communities. c/drugs serves as the central Hub, branching off into more substance-specific discussions from there.

This also includes the establishment of some basic rules for this community:

Rules

(These rules apply across all communities in the c/Drugs network.)

No Sourcing - Do not request sources of any drugs at any time. This includes unregulated research chemicals. Any attempts, including "hit me up in DMs" type of requests, will result in a ban. This rule is necessary to keep this community open.

Harm Reduction - Do not recommend inherently dangerous doses or combinations of substances, or otherwise encourage behavior more risky than drug use already is by default. Clear attempts at causing intentional harm will result in a ban.

Avoid Dangerous Recommendations - Avoid recommending substances that have a reasonable chance of causing considerable harm to the user. For example, DPH, inhalants, or opioids. This rule is necessary to conform with Lemmy.World's Terms of Service. Posts violating this rule will be removed.

No Minors - Users under 18 years old are not permitted to use this community.

☺c/MDMA Rules☺

• Keep It Friendly - Be kind to your fellow humans. Disagreements, even impassioned ones, are fine. If you bring it down to the level of personal insults or excessive hostility, your posts may be removed. You may be banned in especially severe instances such as racism, sexism, Nazism, Zionism, etc.

Hello, I am building a (still-expanding) network of drug discussion communities, which currently includes:

Communities

• c/drugs - General Drug Discussion (Main / Central Community)
• c/weed - Cannabis Discussion
• c/psy - Psychedelic Discussion
• c/drank - Alcohol Discussion
• c/opi - Opiate Discussion

I've gotten these communities to a point I'm happy with (except c/drank but I'll be getting to that one soon. I had trouble finding an icon for it). I've also had no real trouble moderating them (Lemmy moderation is usually easy, most people here are nice).

So I'd like to request a community which appears to have been created, and then immediately locked down by, the user who made it:

• c/mdma

The only post, from 3 years ago, says "This community is currently awaiting the outcome of an agreement which will decide this communities future." Not sure what that's about but I'd like to get it running as a MDMA discussion sub in the style of these other subs. Thank you!

[P]lant scientists Paula Berman and Janka Höfer and their team set out to map and rebuild the biochemical pathways behind these compounds.

They identified the key genes used by two plants – Psychotria viridis and Acacia acuminata – to make DMT, and the step-by-step chemical pathways involved in producing the compound.

Then, they combined these with genes and pathways already known from psychedelic mushrooms (Psilocybe cubensis) and the cane toad (Rhinella marina), added supporting enzymes from rice and cress, then genetically introduced the combined genetic toolkit and kaboodle into tobacco plants (Nicotiana benthamiana).

The tobacco was chosen not because of its own drug production, but because it's basically the lab rat of plant species, with its fast growth.

Finally, the team carefully monitored the plant's production of five psychedelic tryptamines: DMT originally from plants; psilocin and psilocybin from mushrooms; and bufotenin and 5-MeO-DMT from toads.

The modified tobacco plants were found to produce all five compounds simultaneously. Because the different production pathways compete for the same resources, some compounds were produced in lower quantities than in their original sources.

However, the production was high enough to suggest that with a bit more tweaking, the system could function as a biological tryptamine factory for researchers.

[P]lant scientists Paula Berman and Janka Höfer and their team set out to map and rebuild the biochemical pathways behind these compounds.

They identified the key genes used by two plants – Psychotria viridis and Acacia acuminata – to make DMT, and the step-by-step chemical pathways involved in producing the compound.

Then, they combined these with genes and pathways already known from psychedelic mushrooms (Psilocybe cubensis) and the cane toad (Rhinella marina), added supporting enzymes from rice and cress, then genetically introduced the combined genetic toolkit and kaboodle into tobacco plants (Nicotiana benthamiana).

The tobacco was chosen not because of its own drug production, but because it's basically the lab rat of plant species, with its fast growth.

Finally, the team carefully monitored the plant's production of five psychedelic tryptamines: DMT originally from plants; psilocin and psilocybin from mushrooms; and bufotenin and 5-MeO-DMT from toads.

The modified tobacco plants were found to produce all five compounds simultaneously. Because the different production pathways compete for the same resources, some compounds were produced in lower quantities than in their original sources.

However, the production was high enough to suggest that with a bit more tweaking, the system could function as a biological tryptamine factory for researchers.

cross-posted from: https://lemmy.world/post/43854594

A “No-Veg” method flips plants straight to 12/12, trading smaller individual yields for higher annual output and a dramatic jump in top-shelf buds.

A “No-Veg” method flips plants straight to 12/12, trading smaller individual yields for higher annual output and a dramatic jump in top-shelf buds.

cross-posted from: https://lemmy.world/post/43292713

Abstract

This study revisits the hypothesis that Claviceps purpurea (Fr.) Tul., a fungus infecting cereals and producing ergot alkaloids (EAs), was the psychedelic agent in kykeon, the sacred elixir of the Eleusinian Mysteries. Although archaeological evidence supports this link, experimental data confirming the transformation of toxic ergopeptides into psychoactive lysergic acid amide derivatives in putative ancient preparations remain limited. The potential hydrolysis products of ergot were investigated using a technique that could have been readily applied by the priestesses of Eleusis, notably reacting in lye. Pulverized sclerotia were refluxed in solutions of lye and in distilled water. Samples obtained after liquid-liquid extractions were analyzed with 1H-NMR and UHPLC/Q-TOF-HRMS. The 1H NMR spectra demonstrated conversion of toxic ergopeptides, present in control samples but absent at all reaction times in 5% w/v ergot treated with pH 12.5 lye, where characteristic peaks for lysergic acid amide (LSA; ergine) and isolysergic acid amide (iso-LSA; isoergine; erginine) appeared. UHPLC/Q-TOF-HRMS quantitation confirmed this conversion, yielding 0.54 mg LSA and 0.48 mg iso-LSA per gram of ergot at 120 min. The chemical transformation of toxic EAs to psychoactive compounds, utilizing ancient technology, was demonstrated and supports the “psychedelic Eleusis” hypothesis.

Abstract

This study revisits the hypothesis that Claviceps purpurea (Fr.) Tul., a fungus infecting cereals and producing ergot alkaloids (EAs), was the psychedelic agent in kykeon, the sacred elixir of the Eleusinian Mysteries. Although archaeological evidence supports this link, experimental data confirming the transformation of toxic ergopeptides into psychoactive lysergic acid amide derivatives in putative ancient preparations remain limited. The potential hydrolysis products of ergot were investigated using a technique that could have been readily applied by the priestesses of Eleusis, notably reacting in lye. Pulverized sclerotia were refluxed in solutions of lye and in distilled water. Samples obtained after liquid-liquid extractions were analyzed with 1H-NMR and UHPLC/Q-TOF-HRMS. The 1H NMR spectra demonstrated conversion of toxic ergopeptides, present in control samples but absent at all reaction times in 5% w/v ergot treated with pH 12.5 lye, where characteristic peaks for lysergic acid amide (LSA; ergine) and isolysergic acid amide (iso-LSA; isoergine; erginine) appeared. UHPLC/Q-TOF-HRMS quantitation confirmed this conversion, yielding 0.54 mg LSA and 0.48 mg iso-LSA per gram of ergot at 120 min. The chemical transformation of toxic EAs to psychoactive compounds, utilizing ancient technology, was demonstrated and supports the “psychedelic Eleusis” hypothesis.

cross-posted from: https://lemmy.world/post/42316499

Psilocybin was the most popular, followed (surprisingly) by Amanita muscaria, then MDMA, then LSD.

That means 3.7% of the American population has microdosed. If you ask me, we have to up those numbers, and those dosages... it's not a bad start, but I'm worried that it's a way to cheapen the psychedelic experience, lending it to "enhancing productivity" instead of rewiring your psyche and breaking down social constructs.

If it helps people, it can't be a bad thing. I just hope it doesn't stop at "micro" for most people.

What do you all think?

Psilocybin was the most popular, followed (surprisingly) by Amanita muscaria, then MDMA, then LSD.

That means 3.7% of the American population has microdosed. If you ask me, we have to up those numbers, and those dosages... it's not a bad start, but I'm worried that it's a way to cheapen the psychedelic experience, lending it to "enhancing productivity" instead of rewiring your psyche and breaking down social constructs.

If it helps people, it can't be a bad thing. I just hope it doesn't stop at "micro" for most people.

What do you all think?

Community Intro

This community is now back and open for posting! Thanks to the Lemmy.world admins for granting me the mod role here.

My current goal for this community is for it to serve as the main, central community branching out into smaller, more substance-specific communities. Currently, the network is small, including:

• c/weed - Cannabis Discussion
• c/psy - Psychedelic Discussion
• c/mdma - MDMA / Ecstasy Discussion
• c/drank - Alcohol Discussion
• c/opi - Opiate Discussion

I'm also open to suggestions for other communities, and in need of people to help moderate them. (Lemmy usually doesn't require much, if any, moderation, but I'd still like to have a team of people anyway.)

Rules

The most critical rule for this and all related communities is NO SOURCING. Asking where to buy any drugs, including unregulated drugs, even in a "hey hit me up in DM's" sort of way, could get us shut down or worse. This is the regular old clearnet internet, the mods here and the Lemmy.world admins still have to worry about the law. It's not a moral thing and it is prohibition bullshit, but it's the world we've got for now, so work with us there please.

Aside from that, just be as kind as you can be to the people who are kind to you, don't recommend that people do anything which is more dangerous than drug use already inherently is (ie dangerous doses or combos), and we'll be good. (Note that these topics can still be discussed, people just shouldn't be encouraged to participate in behaviors which could cause them harm.)

Also, minors are not permitted to use c/Drugs or any of our networked communities. I don't think there are too many minors on Lemmy, but doesn't hurt to clarify that anyway.

Welcome again to c/Drugs!

Concept Credit

The concept and structure for the network of drug-related communities comes from my experience on 420chan over a decade ago (I am old). For those unfamiliar with 420chan, it was nothing like 4chan. It was the old internet, so it still had its problems (ie racism, which obviously won't be permitted here). But for example, it had a dedicated (supportive) transgender board and issued permanent bans to people who posted loli content. By old-internet-anonymous-imageboard standards, it wasn't the worst place to hang out.

It was also an important place for a weird young person like I was at the time, who wanted to know more about aspects of the world which were presented as taboo, but also wanted to know what was genuinely unsafe.

So thank you to Kirtaner and the mod team for all those fun years. When Kirt gets out of prison (for allegedly hacking the Texas Republican Party), if he wants me to stop using the old 420chan icons, just let me know. I just figured I'd do this because there are no plans to revive the original site and it serves an important function I think.

Post stuff here when you're high. Anything. Have fun with it.

Sort comments by "New" for best experience.

This, to me, is much more concerning than the news about an eventual-probably rescheduling. Having to buy seeds on the darkweb, or at state-legal dispensaries assuming they continue selling them, would be a huge stumbling block to homegrowers. I assume that's the intent by whoever lobbied for this move.

The good news is, it doesn't go into effect until November 2026. Stock up your seed banks before then just in case, I'd say.

Clones and tissue cultures may end up being a loophole to this policy as well, but that's apparently legally unclear for now. (Which, at least for cannabis, usually translates to "as good as legal".)

This article by Vincente LLP, a cannabis law firm, covers what rescheduling does and doesn't mean.

It's also important to note that Trump did not directly reschedule cannabis (something which, as I understand it, the Controlled Substances Act actually does give the Executive Branch unilateral authority to do) but just directed the Attorney General to "complete the rulemaking progress" related to rescheduling. It might come soon, or it might be political theater and get forgotten about.

My assumption is that this is a result of lobbying by major corporations, and it will happen.

As a Californian, I expect the best case (and most likely) scenario is that nothing meaningfully changes except some benefits for MSO's (who usually don't deserve benefits because they grow trash weed, except 710Labs). I used to work in the cannabis industry (and may again soon), and there doesn't seem to be much apparent alarm by brands. But maybe they're just playing it cool.

I expect the worst case scenario is Malboro selling light dep garbage and hotdog-water distillate at Walgreens or Walmart. I'm not sure how this will (or won't) affect other states. The Malboro outcome might be more likely in states which have a weak cannabis market.

An estimated 60% of California's cannabis sales are thought to be on the legacy market ("illegal" by illegitimate laws). Unless it's purely an issue of price with little regard to quality - which I don't think it is - then I don't see either outcome changing that.

I think the goal should obviously be descheduling cannabis. No government has the authority to legislate what you do with your own body.

Thoughts?

Posted here 14 / 15 days ago with requests for those subreddits. Admins have ignored my request but responded to requests by others made more recently.

At least give me a "no" if it's a no, please. My account here doesn't have a ton of activity, but my u/7101334 account on Reddit is very active. I want to use Lemmy more and Reddit less, but if there's an apparent stigma towards drug users here, let me know so I can pass and keep looking for a better place.

It has no moderators at all despite still being open to posts. Pretty dead but maybe I can make it not-dead. Trying to make a little network stemming out from ![email protected] if that request is approved.

Sourcing - even sourcing legal cannabis, even federally legal like Delta-8-THC - would not be allowed. I would try to find some additional mods from the active users.

I've been a member of drug discussion boards for over a decade and have a pretty good understanding of what's legally allowed (basically any discussion short of step-by-step synthesis instructions) and what's not (sourcing any drugs, even 'grey area' ones).

![email protected] is shut down because...

This community is participating in a blackout against Lemmy for allowing free access to their API with no charge, rendering it affordable for third-party app developers to continue their services. The lack of prohibitive cost makes it easy to mod from mobile, promotes innovation, and gives unlimited user choice, and effectively opens up a significant portion of the culture we’ve all come to appreciate. Indeed, every third party app developer on Lemmy made essentially the same statement: “I don’t have to shut down the app.” Apps can also show ads which is a primary source of revenue. So not only do they not have to pay exorbitant fees, they can even mitigate those fees with ads.

And the current mod is inactive, and has been for 2 years now. I'd like to be made mod there and appoint other mods from active users in the community, considering the sub was pretty active before it got locked down.