Spyke

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memes

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Health "care"

Don't give doctors a bad name like that. They work their asses off to help people and go many years being overworked and underpaid to do it

It's the insurance companies that reap the benefits of people's misfortune

world

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Chinese scientists develop cure for diabetes, insulin patient becomes medicine-free in just 3 months

I literally worked in a research lab working on islet cell therapies for diabetes in the US. This has actually been done many times before with cells from cadavers. It has been successful, although most the of the time the person reverts back after a few years

The issues we were trying to solve in the lab were

  1. Finding a good place to transplant where the cells will last: Implanting in the hepatic region (liver), which is the most common place to implant, is toxic to the cells over time hence only lasting 3-5 years. The cells need a really good blood supply and the volume you're transplanting can't be easily transplanted in the pancreas or kidney capsules (where many successful studies were performed in mice and rats)

  2. Being able to consistently make a high volume of stem cells that are fully grown into insulin producing cells: Cadaver cells usually require 3-5 donors for 1 person and require the receiver to be on lifelong immunosuppresors due to the immune response. Depending on the kind of stem cells, the patient may still even need immunosuppresors due to the cell type you're converting from

All this the say - the article says nothing about where the cells where transplanted, where they came from, or whether the person has Type 1 or Type 2 diabetes. Although it is still a feat, it is likely not the first time it has been done, and we're still a long ways off from a cure

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Considering today’s film/TV ratings, do you think they reflect audience fatigue, industry shifts, societal changes, and new viewing habits, not quality drop?

It's definitely a drop in quality. Just look at what is out in movie theaters these days. 90% of the movies are either sequels, marvel movies, or live action remakes of films that were already made. The amount of original storytelling or unique content has dropped rapidly in the past 5 years. As someone who grew up loving going to the movie theater, it makes me so sad, and I rarely go anymore.

Whether you like or hate Barbie or Oppenheimer, they were pretty much some of the only completely brand new high production value movies that came out in the last year, which I believe is part of why they were so popular. People are craving originality, even if a lot of them don't realize it

world

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More people getting kidney failure in Singapore

For those who dont feel like reading the whole article, here's why:

"Much of the increase in kidney failure is caused by an ageing population. When age is taken into account, the number of people with kidney failure as a proportion of the population has remained fairly stable over the past decade, according to data from the registry."

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How did you get your job? Any advice?

It sounds like if you're trying all of this and it's still not working, something about the way you're selling yourself isn't working. Have you tried changing your resume to better match different job descriptions? Try having someone give you feedback on the way you interview. Are you coming on too strong? Maybe you dont have enough specific examples in your answers or too many specifics and not enough leadership/direction. I would also use LinkedIn if you're not already

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Hot tub owners: any tips? any regrets?

If you're going to get one, highly recommend getting 240V instead of 110v/plug and play type. 240V are the only ones that can really keep up with the heat and give you that real jet feel in the tub.

If possible, keep it somewhere covered. We have it in our covered patio, which allows us to get use of it in any kind of weather and prevents mosquitos/other bugs coming around.

Chemical balancing can be pretty tough, we mostly keep a steady supply of bleach around to make sure it's staying clean. One issue we had was the test strips never seemed to say the water was hard enough so we kept adding calcium hardner, but it ended up precipitating and making a rough coating on the seats (eventually we were able to clean it off). Ended up deciding it wasn't a big deal if some values are out of range on the test strips as long as the stuff to keep people safe is balanced (ie chlorine)

movies

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What happened to "stoner" comedies?

Don't forget about all the Harold and Kumars, pineapple express, basically every other movie with Seth rogan, all the bill and Ted's, Project x, role models, tropic thunder, horrible bosses, 21 jump street, etc. Some of these are also older, but I do think there are a lot more out there than you're listing

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Engineers vs Physicists

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The funny thing is, the very first thing engineers learn in almost any class is significant figures and to make sure an answer makes sense in a real life scenario. Obviously not everyone is the same in terms of how they apply things, but engineers are definitely taught not to do stuff like that

memes

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Every App is a dating app

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Imagine if this meme said "Being rich is easy, if your Jewish enough " with a picture of a guy in a yamuka. How is that not playing into the stereotype? The whole point of the joke is that this is a stereotype of the culture

memes

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Flux pricing

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I feel like Jimmy johns and chick fil a are the only truly fast restaurants anymore. For JJ you do have to go inside, but they often make your sandwich and complete payment in less than a minute, maybe 5 minutes max.

Meanwhile I've been to other drive throughs where even with very few people in line, it somehow takes 10/15 mins to get your meal. Plus, it's often incorrectly made and expensive

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Score

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Pretty sure scalloped doesn't necessarily mean to bake in cream sauce. It refers to the way they are cut - concentric circles or semi circles to look like scallops (the fish). So although they may look like scallops, there's no fish in the dish at all.