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First Potential Medical (Non-dye) Solution for Gray Hair (Early trial summary in post body)

Edit: This is a genuinely interesting story, y’all downvoters are just wrong. 🤭

Anti-gray hair topical via melanogenesis rescue: proteoglycan mix restored melanogenesis-associated transcription factor expression 3.7x in human melanocytes, with 4x synergistic antioxidant effect.

The latter is interesting because while H₂O₂ is a normal byproduct of cellular metabolism, its metabolism by catalase expression drops significantly with age. This means the accumulated H₂O₂ (a ROS) literally bleaches the melanin from inside the follicle using the same mechanism that cosmetic bleaching products lighten hair.

Problems with this study:

  • In vitro only
  • Manufacturer-funded
  • Arbitrarily women-labeled despite gender agnostic study
  • Cosmetic-classified to dodge RCT standards and market to anti-pharma segment

https://pmc.ncbi.nlm.nih.gov/articles/PMC12846973/

View original on lemmy.world
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First Potential Medical (Non-dye) Solution for Gray Hair (Early trial summary in post body) | Spyke