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Why I moved from GrapheneOS to iodéOS on my Google Pixel
Android Auto did take some setup for me, but it works just fine. It is not too much of a hassle to setup if it is installed through the GrapheneOS store. I did have to return to stock Android for a time as I could not get the GPS to work properly, but it worked for the longest time at first, and it has been working working just fine for a while now. I use Ally, DIscover, and American Express for my banking and credit card needs, and I have never even had the slightest amount of trouble doing so. My app for work has never been a problem, nor has any app ever been a problem besides Android Auto at first. I do not even use the Google Play Store; I use the Aurora Store and F-Droid.